Correction to “Deletion of Dux ameliorates muscular dystrophy in mdx mice by attenuating oxidative stress via Nrf2”

Abstract

Sun SY, Zhai W, Zhang RX, Cai N. Deletion of Dux ameliorates muscular dystrophy in mdx mice by attenuating oxidative stress via Nrf2. The FASEB Journal. 2024;38:e23771. doi:10.1096/fj.202400195R

In paragraph 1 of the “Materials and Methods” section, the text “C57BL/10ScSnJ mice (WT), C57BL/10ScSn-Dmdmdx/J mice (mdx) and Dux^−/− mice were provided by The Jackson Laboratory (Bar Harbor, ME, USA).” was incorrect. This should have read: “C57BL/10ScSnJ mice (WT) and C57BL/10ScSn-Dmdmdx/J mice (mdx) were provided by The Jackson Laboratory (Bar Harbor, ME, USA), Dux^−/− mice were provided by Shanghai Model Organisms Center, Inc. (Shanghai, China).”

In paragraph 8 of the “Materials and Methods” section, the text “Dux, 5′-ATGGCCCTCCCGACACCCT-3′ (forward), 5′-ATGCCCGGGTACGGGTTCCGCTCAAAG-3′ (reverse); Nrf2, 5′-TAGAGTCAGCAACGTGGAAG-3′ (forward), 5′-TATCGAGGCTGTGTCGACTG-3′ (reverse)” was incorrect. This should have read: “Dux, 5′-AACCCACGACCAGGCTTTG-3′ (forward), 5′-CCGAGCTCTTCGGTTTTGAA-3′ (reverse); Nrf2, 5′-CTTTAGTCAGCGACAGAAGGAC-3′ (forward), 5′-AGGCATCTTGTTTGGGAATGTG-3′ (reverse)”.

In paragraph 9 of the “Materials and Methods” section, the Invitrogen antibody (item number PA5-114311) was used to detect Dux in this study. PVDF membranes were incubated with this antibody (dilution ratio 1:1000) at 4°C overnight.

For muscle histology, we claim that: Muscle tissues were isolated from mice and stained according to HE and Masson kit instructions. Consistent with a previously published report (1), the gastrocnemius muscle of mdx mice had a significant inflammatory infiltrate and collagen deposition. More importantly, all images in this article are unedited and original.

We apologize for this error.