Drugs and ANCA - an atypical association.

IF 1.4 4区 医学 Q3 RHEUMATOLOGY ARP Rheumatology Pub Date : 2024-07-01 DOI:10.63032/PXUT9006
Tiago Beirão, Beatriz Samões, Catarina Rua, Romana Vieira, Joana Abelha-Aleixo, Patricia Pinto, Flavio Costa, Diogo Fonseca, Margarida Mota, Catarina Amorim Meireles, Taciana Videira
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Abstract

Eosinophilic vasculitis is a rare condition due to vascular damage and infiltration of eosinophils into tissues. Antineutrophil cytoplasmic antibody (ANCA), like perinuclear ANCA (p-ANCA), is common in the context of systemic vasculitis, but its association with illicit drug use is unusual. This case report showcases a distinctive scenario featuring a positive pANCA, prompting a meticulous examination of the interplay between vasculitic manifestations and drug abuse.

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药物与 ANCA--非典型关联。
嗜酸性粒细胞性血管炎是一种罕见的疾病,是由于血管损伤和嗜酸性粒细胞浸润组织所致。抗中性粒细胞胞浆抗体(ANCA)与核周 ANCA(p-ANCA)一样,在全身性血管炎中很常见,但与非法药物使用有关的情况并不多见。本病例报告展示了一种以 pANCA 阳性为特征的独特情况,促使人们对血管炎表现与药物滥用之间的相互作用进行细致的研究。
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