Clinical perspectives: Takotsubo cardiomyopathy

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Internal Medicine Journal Pub Date : 2024-09-09 DOI:10.1111/imj.16493
Jayant Ravindran, David Brieger
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Abstract

Takotsubo syndrome is a condition characterised by temporary acute left ventricular dysfunction with regional wall abnormalities extending beyond a single coronary artery territory. Initially thought to be benign, this condition, which is challenging to distinguish from acute coronary syndrome, has substantial morbidity and mortality. The mechanism behind this condition remains elusive, but multiple theories have been proposed. Although beta blockers and angiotensin-converting enzyme inhibitors are used as treatments for left ventricular dysfunction, currently, there are no randomised controlled trials to support their use. In this paper, we review the latest evidence regarding aetiologies, pathophysiology, diagnostic criteria, prognosis, complications and management of Takotsubo syndrome.

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临床视角:塔克氏心肌病
高突波综合征是一种以暂时性急性左心室功能障碍为特征的疾病,其区域性室壁异常超出了单一冠状动脉区域。最初被认为是良性的,但这种难以与急性冠状动脉综合征区分的病症具有很高的发病率和死亡率。这种病症背后的机制仍然难以捉摸,但已提出了多种理论。虽然β受体阻滞剂和血管紧张素转换酶抑制剂被用作治疗左心室功能障碍的药物,但目前还没有随机对照试验支持使用这些药物。在本文中,我们回顾了有关塔克次氏综合征的病因、病理生理学、诊断标准、预后、并发症和治疗的最新证据。
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来源期刊
Internal Medicine Journal
Internal Medicine Journal 医学-医学:内科
CiteScore
3.50
自引率
4.80%
发文量
600
审稿时长
3-6 weeks
期刊介绍: The Internal Medicine Journal is the official journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP). Its purpose is to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. The Journal also has a major role in continuing medical education and publishes review articles relevant to physician education.
期刊最新文献
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