Genomic-Based Early Detection Screening: A Literature Review of Prospective Trials and Emerging Strategies for Gastrointestinal Cancers.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL Cureus Pub Date : 2024-09-07 eCollection Date: 2024-09-01 DOI:10.7759/cureus.68881
Eemon Tizpa, Kaveh Sharzehi, Nima Nabavizadeh
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Abstract

Numerous genomic-based early detection screening tests are being developed. These tests have the potential to revolutionize current single-organ screening paradigms, especially in gastrointestinal cancers. In this review, we underscore the performance of these genomic-based early detection tests based on prospective clinical trials. Moreover, we discuss a professional advancement for gastroenterologists in the diagnostic assessment of individuals who are cancer signal positive.

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基于基因组的早期检测筛查:基于基因组的早期检测筛查:前瞻性试验文献综述与胃肠道癌症的新兴策略》。
目前正在开发许多基于基因组的早期检测筛查试验。这些检测方法有望彻底改变目前的单器官筛查模式,尤其是胃肠道癌症的筛查。在这篇综述中,我们根据前瞻性临床试验强调了这些基于基因组的早期检测试验的性能。此外,我们还讨论了胃肠病学家在对癌症信号阳性者进行诊断评估方面的专业进步。
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