Recent Advances in Organocatalytic Enantioselective Reactions of α‐Functionalized Propargylic Alcohols

IF 2.8 4区 化学 Q1 CHEMISTRY, ORGANIC Asian Journal of Organic Chemistry Pub Date : 2024-09-03 DOI:10.1002/ajoc.202400377
Yan Xia, Meiwen Liu, Wenjun Li, Pengfei Li
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Abstract

Owing to their unique properties, propargylic alcohols have been recognized as one of the most attractive synthons in the field of organic synthesis. Particularly, with the aid of auxiliary group, the α‐functionalized propargylic alcohols have been frequently involved in the organocatalytic enantioselective substitutions, conjugate additions, annulations and related reactions in recent years. Accordingly, the present review highlights recent advancements in the application of α‐functionalized propargylic alcohols in the field of asymmetric organocatalysis, which is organized according to the type of auxiliary group.
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α官能化丙炔醇的有机催化对映体选择性反应的最新进展
丙炔醇因其独特的性质,已被公认为有机合成领域最具吸引力的合成物之一。特别是近年来,在辅助基团的帮助下,α 官能化丙炔醇经常参与有机催化的对映选择性取代、共轭加成、环化及相关反应。因此,本综述重点介绍了 α 官能化丙炔醇在不对称有机催化领域的最新应用进展,并根据辅助基团的类型进行了分类。
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来源期刊
CiteScore
4.70
自引率
3.70%
发文量
372
期刊介绍: Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.
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