{"title":"Determination of the Rosmarinic Acid Content in Mentha piperita L. Leaves by HPLC","authors":"V. A. Kurkin, M. A. Kazakova, A. R. Mubinov","doi":"10.1007/s11094-024-03191-1","DOIUrl":null,"url":null,"abstract":"<p>An HPLC method for the quantitative determination of the rosmarinic acid content in leaves of peppermint (<i>Mentha piperita</i> L.) was developed. The content of the dominant phenylpropanoid rosmarinic acid in leaves of <i>M. piperita</i> varied from 2.01 ± 0.03% to 5.54 ± 0.05%. The error of a single determination of the rosmarinic acid content in <i>M. piperita</i> leaves was ±9.66% at a confidence probability of 95%.</p>","PeriodicalId":19990,"journal":{"name":"Pharmaceutical Chemistry Journal","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceutical Chemistry Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11094-024-03191-1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
An HPLC method for the quantitative determination of the rosmarinic acid content in leaves of peppermint (Mentha piperita L.) was developed. The content of the dominant phenylpropanoid rosmarinic acid in leaves of M. piperita varied from 2.01 ± 0.03% to 5.54 ± 0.05%. The error of a single determination of the rosmarinic acid content in M. piperita leaves was ±9.66% at a confidence probability of 95%.
期刊介绍：
Pharmaceutical Chemistry Journal is a monthly publication devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including:
methods of synthesis;
results of pharmacological, toxicological, and biochemical studies;
investigation of structure - activity relationships in prediction of new compounds;
methods and technical facilities used; and
problems associated with the development of ecologically safe and economically feasible methods of industrial production.
In addition, analytical reviews of the international literature in the field provide coverage of the most recent developments around the world.
Pharmaceutical Chemistry Journal is a translation of the Russian journal Khimiko-Farmatsevticheskii Zhurnal. The Russian Volume Year is published in English from April.
All articles are peer-reviewed.
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