The current and future cancer burden in the Gulf Cooperation Council (GCC) countries

IF 2.9 2区 医学 Q2 ONCOLOGY Cancer Medicine Pub Date : 2024-09-16 DOI:10.1002/cam4.70141
Saleh A. Alessy, Saleh A. Alqahtani, Jerome Vignat, Amid Abuhmaidan, Amani E. L. Basmi, Najla Al Lawati, Ameera Ali A-Nooh, Wael Shelpai, Samar Alhomoud, Ali Al-Zahrani, Freddie Bray, Ariana Znaor
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Abstract

Background

Cancer is a leading cause of morbidity and mortality in the Gulf Cooperation Council (GCC) countries. This study aims to provide cancer incidence and mortality estimates in 2020 in the GCC countries alongside future projections for 2040 to shape cancer control policy in the region.

Methods

The estimated numbers of new cancer cases and deaths were extracted from the GLOBOCAN database developed by the International Agency for Research on Cancer; new cancer cases, cancer deaths, and corresponding age-standardized incidence and mortality rates for the year 2020 are presented.

Results

An estimated 42,475 new cancer cases and 19,895 deaths occurred in the GCC countries in 2020, with corresponding age-standardized incidence and mortality rates of 96.5 and 52.3 per 100,000, respectively. Female breast (16%), colorectal (13%), and thyroid (9%) were the most common types of cancer in the GCC countries, accounting for almost 40% of all cancer incidence. Colorectal (14%) followed by breast cancer (9%) were the leading causes of cancer death, though the magnitude of rates of the major cancer types varied substantially across the GCC countries. Even if we assume rates in the region will remain unchanged over the next two decades, the cancer burden in the GCC will increase by 116% (Saudi Arabia) to 270% (Qatar), reaching nearly 104,000 cancer cases by the year 2040.

Conclusion

The sharp increase in the estimated cancer incidence and mortality predicted over the next decades in the region requires workforce and financial planning for the healthcare systems in the constituent countries, alongside broader strengthening of national cancer prevention and control efforts.

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海湾合作委员会(GCC)国家当前和未来的癌症负担
背景 癌症是海湾合作委员会(GCC)国家发病和死亡的主要原因。本研究旨在提供海湾合作委员会国家 2020 年的癌症发病率和死亡率估计数以及 2040 年的未来预测数,以制定该地区的癌症控制政策。 方法 从国际癌症研究机构(International Agency for Research on Cancer)开发的 GLOBOCAN 数据库中提取新发癌症病例和死亡病例的估计数字;列出 2020 年新发癌症病例、癌症死亡病例以及相应的年龄标准化发病率和死亡率。 结果 估计 2020 年海湾合作委员会国家将新增 42,475 例癌症病例和 19,895 例死亡病例,相应的年龄标准化发病率和死亡率分别为每 10 万人 96.5 例和 52.3 例。女性乳腺癌(16%)、结直肠癌(13%)和甲状腺癌(9%)是海湾合作委员会国家最常见的癌症类型,占所有癌症发病率的近 40%。结肠直肠癌(14%)和乳腺癌(9%)是导致癌症死亡的主要原因,但海湾合作委员会国家主要癌症类型的发病率差异很大。即使我们假设该地区的癌症发病率在未来 20 年内保持不变,海湾合作委员会的癌症负担也将增加 116%(沙特阿拉伯)至 270%(卡塔尔),到 2040 年将达到近 104,000 例癌症病例。 结论 预计未来几十年该地区癌症发病率和死亡率将急剧上升,这就要求各成员国的医疗保健系统进行劳动力和财务规划,同时更广泛地加强国家癌症预防和控制工作。
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来源期刊
Cancer Medicine
Cancer Medicine ONCOLOGY-
CiteScore
5.50
自引率
2.50%
发文量
907
审稿时长
19 weeks
期刊介绍: Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas: Clinical Cancer Research Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations Cancer Biology: Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery. Cancer Prevention: Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach. Bioinformatics: Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers. Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.
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