{"title":"Bi2O3-Doped Bioglass 45S5 for Medical Use","authors":"D. N. Grishchenko, M. A. Medkov","doi":"10.1134/s003602362460179x","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>Bioglass 45S5 was doped with bismuth oxide in concentrations up to 40 wt %. The amorphism of the synthesized glasses was confirmed by X-ray powder diffraction. The influence of Bi<sub>2</sub>O<sub>3</sub> on the properties of the bioactive glass was studied. In a series of samples containing 0 to 40 wt % bismuth oxide, the glass characteristics change as follows: pH in the model medium decreases from 7.84 to 7.46 upon glass leaching; radiopacity increases from 1150 HU to values above 11 000 HU; percent chemical degradation drops from 1.299% to 0.424%; bioactivity decreases in the range 0–10 wt % Bi<sub>2</sub>O<sub>3</sub> and is absent in the range 20–40 wt % Bi<sub>2</sub>O<sub>3</sub>. The bioactive glasses containing up to 10 wt % Bi<sub>2</sub>O<sub>3</sub> can find application in reconstructive surgery. They have radiopaque and bioactive properties. The bioactive glasses containing 20–40 wt % Bi<sub>2</sub>O<sub>3</sub> have high radiopacity and chemical durability, and only weakly affect pH when dissolved. They may be candidate radiomodifier materials for the radiation therapy of malignant neoplasms.</p>","PeriodicalId":762,"journal":{"name":"Russian Journal of Inorganic Chemistry","volume":"180 1","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Inorganic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1134/s003602362460179x","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
引用次数: 0
Abstract
Bioglass 45S5 was doped with bismuth oxide in concentrations up to 40 wt %. The amorphism of the synthesized glasses was confirmed by X-ray powder diffraction. The influence of Bi2O3 on the properties of the bioactive glass was studied. In a series of samples containing 0 to 40 wt % bismuth oxide, the glass characteristics change as follows: pH in the model medium decreases from 7.84 to 7.46 upon glass leaching; radiopacity increases from 1150 HU to values above 11 000 HU; percent chemical degradation drops from 1.299% to 0.424%; bioactivity decreases in the range 0–10 wt % Bi2O3 and is absent in the range 20–40 wt % Bi2O3. The bioactive glasses containing up to 10 wt % Bi2O3 can find application in reconstructive surgery. They have radiopaque and bioactive properties. The bioactive glasses containing 20–40 wt % Bi2O3 have high radiopacity and chemical durability, and only weakly affect pH when dissolved. They may be candidate radiomodifier materials for the radiation therapy of malignant neoplasms.
期刊介绍：
Russian Journal of Inorganic Chemistry is a monthly periodical that covers the following topics of research: the synthesis and properties of inorganic compounds, coordination compounds, physicochemical analysis of inorganic systems, theoretical inorganic chemistry, physical methods of investigation, chemistry of solutions, inorganic materials, and nanomaterials.
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