Challenging the Chronic Perverse Bias in Prosthetic Valve Design: A Pathway Opens for Advanced Mechanical Valves.

Abstract

Objective: -In vitro evaluation of several prototype mechanical valves compared to present-day SAVR prosthetic valves. Method: -simulated normal cardiac pressures and flows -gravity pressure head column tester flows -recorded valve hydrodynamics and kinematics Results: -valves superior in performance to clinical controls Conclusions: -Prototype MHV candidates outperform the closing performance of present-day SAVR prosthetic valves, including bioprosthetic control.