Identifying the Role of Flow-Mediated Dilatation Assessment in Acute Coronary Syndromes: A Systematic Review.

IF 2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Cardiology in Review Pub Date : 2024-09-10 DOI:10.1097/CRD.0000000000000768
Georgios Zormpas, Aristi Boulmpou, Victoria Potoupni, Fotios Siskos, Nikoleta Chatzipapa, Nikolaos Fragakis, Michael Doumas, George Kassimis, Vassilios Vassilikos, Christodoulos E Papadopoulos
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Abstract

In the context of the global burden of cardiovascular disease, the development of novel, patient-targeted diagnostic and therapeutic strategies is of paramount importance. Acute coronary syndromes (ACS) comprise a subset of cardiovascular disease, with constantly increasing prevalence requiring urgent attention. Flow-mediated dilatation (FMD), a noninvasive method for the evaluation of endothelial function, has been previously implemented in patients with ACS. A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was conducted in order to identify all relevant studies assessing the implementation of FMD among patients with ACS. Our review reflects an effort to present all available data regarding the role of FMD to date, a valuable noninvasive and easy accessible diagnostic tool, in the prognosis of patients with ACS. FMD evaluation in patients with ACS reveals a decline in values, indicative of the presence of endothelial function among this distinct patient group. FMD has also been used to assess the response to various treatments, as well as to predict major adverse cardiovascular events. Dynamic responses to interventions highlights its potential in the evolving field of interventional cardiology.

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确定急性冠状动脉综合征中血流介导的扩张评估的作用:系统性综述。
在全球心血管疾病负担日益加重的背景下,开发新型的、以患者为目标的诊断和治疗策略至关重要。急性冠状动脉综合征(ACS)是心血管疾病的一个分支,其发病率不断上升,亟需引起重视。血流介导的扩张(FMD)是一种评估内皮功能的无创方法,以前曾在 ACS 患者中使用过。为了确定所有评估 ACS 患者 FMD 实施情况的相关研究,我们按照《系统综述和元分析首选报告项目》指南进行了系统综述。我们的综述反映了迄今为止有关 FMD 在 ACS 患者预后中的作用的所有可用数据,FMD 是一种宝贵的无创且易于使用的诊断工具。对 ACS 患者进行的 FMD 评估显示其值有所下降,表明这一特殊患者群体存在内皮功能问题。FMD 还被用于评估对各种治疗的反应,以及预测主要的不良心血管事件。对干预措施的动态反应突显了其在不断发展的介入心脏病学领域的潜力。
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来源期刊
Cardiology in Review
Cardiology in Review CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.60
自引率
0.00%
发文量
76
审稿时长
>12 weeks
期刊介绍: The mission of Cardiology in Review is to publish reviews on topics of current interest in cardiology that will foster increased understanding of the pathogenesis, diagnosis, clinical course, prevention, and treatment of cardiovascular disorders. Articles of the highest quality are written by authorities in the field and published promptly in a readable format with visual appeal
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