A Contemporary Review on Heart Failure with Preserved Ejection Fraction: Epidemiology, Diagnosis, and Management.

IF 2.4 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Current Cardiology Reviews Pub Date : 2024-09-19 DOI:10.2174/011573403X318646240909072055
Mahek Shahid, Ramzi Ibrahim, Abdulbaril Olagunju, Martina Mookadam, Farouk Mookadam
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Abstract

Heart failure with preserved ejection fraction (HFpEF) includes almost half of heart failure cases typified by a specific clinical syndrome. Despite diagnostic and management advances, HFpEF still presents a diagnostic challenge and a paucity of therapies specifically aimed at enhancing survival and improving quality of life is still lacking. This review elucidates the diagnostic complexity of HFpEF, highlighting the use of both subjective and objective criteria within algorithmic frameworks. It also examines the significant impact of comorbidities on the progression of HFpEF. Additionally, we explore the latest evidence on targeting these comorbidities therapeutically, although the benefits to mortality are still limited.

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保留射血分数的心力衰竭的当代综述:流行病学、诊断和管理。
射血分数保留型心力衰竭(HFpEF)包括近一半的心力衰竭病例,以特定的临床综合征为典型特征。尽管在诊断和管理方面取得了进步,但 HFpEF 仍然是诊断方面的一个难题,而且仍然缺乏旨在提高生存率和改善生活质量的专门疗法。本综述阐明了 HFpEF 诊断的复杂性,强调了算法框架中主观和客观标准的使用。它还探讨了合并症对 HFpEF 进展的重大影响。此外,我们还探讨了针对这些合并症进行治疗的最新证据,尽管这些合并症对死亡率的影响仍然有限。
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来源期刊
Current Cardiology Reviews
Current Cardiology Reviews CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.70
自引率
10.50%
发文量
117
期刊介绍: Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.
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