{"title":"Serum protein patterns are associated with future diagnosis of Alzheimer’s disease","authors":"","doi":"10.1038/s43587-024-00723-y","DOIUrl":null,"url":null,"abstract":"Insights into the Alzheimer’s disease blood proteome from a population-based cohort show how the serum levels of certain proteins change prior to diagnosis, how they overlap with signature changes in disease-relevant tissues, and how the association between certain proteins and the disease markedly shifts according to APOE-ε4 carrier status.","PeriodicalId":94150,"journal":{"name":"Nature aging","volume":null,"pages":null},"PeriodicalIF":17.0000,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature aging","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43587-024-00723-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Insights into the Alzheimer’s disease blood proteome from a population-based cohort show how the serum levels of certain proteins change prior to diagnosis, how they overlap with signature changes in disease-relevant tissues, and how the association between certain proteins and the disease markedly shifts according to APOE-ε4 carrier status.
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