Inter Arytenoid Granular Cell Tumor of Larynx-A Rare Case Report.

Abstract

Granular cell tumors (GCTs) are uncommon neoplasms, often originating from Schwann cells, with granular cytoplasm being a hallmark feature. Laryngeal GCTs, comprising 3% to 10% of cases, present diagnostic challenges due to their resemblance to squamous cell carcinoma. We present a case of a 46-year-old male with throat pain, diagnosed with a laryngeal GCT. Histopathological examination and immunohistochemistry confirmed the diagnosis. Laryngeal GCTs typically manifest as small, firm submucosal nodules, posing challenges in differentiation from vocal fold polyps. Diagnosis relies on histological examination, with characteristic features including eosinophilic granular cytoplasm and positive staining for specific markers. Malignant transformation, though rare, necessitates vigilant monitoring and accurate diagnosis. Treatment involves complete surgical excision with long-term follow-up to detect recurrence. This case underscores the importance of awareness and accurate diagnosis in managing laryngeal GCTs, ensuring timely intervention and optimal patient outcomes.