Retrospective Analysis of Treatment Outcomes and Survival Rates in Oral Squamous Cell Carcinoma Patients.

IF 0.7 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-07-31 DOI:10.4103/jpbs.jpbs_297_24
Pankaj Kukreja, Raman Grewal, Annaluru Sri Sasank Tejaswee, Sanjeev Sharma, Anuj Paul Maini, Thara Chandran, Sunil Kumar Gulia
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Abstract

Background: Because of its high rates of morbidity and death, oral squamous cell carcinoma (OSCC) poses a serious threat to world health. To maximize patient care and direct clinical decision-making, it is important to comprehend treatment results and survival rates.

Methods: Treatment results and survival rates for OSCC patients treated at a tertiary care facility between 2010 and 2022 were assessed in this retrospective research. Demographic data, tumor features, treatment options, and follow-up results were all included in the data. The relationships between treatment methods and survival rates were evaluated by statistical analysis.

Results: There were 107 OSCC patients in all. Compared to radiation and chemotherapy, surgery had reduced recurrence rates and greater overall survival rates as the most common treatment option. There were notable variations in survival rates across the various treatment regimens (P < 0.05).

Conclusion: Surgery is the mainstay. Adjuvant treatments, however, are complementary in the management of illness. The significance of customized treatment strategies based on unique patient attributes and tumor features is highlighted by this study in order to maximize results for patients with OSCC. To confirm these results and investigate cutting-edge treatment approaches, more investigation is necessary.

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口腔鳞状细胞癌患者治疗效果和生存率的回顾性分析
背景:口腔鳞状细胞癌(OSCC)发病率和死亡率都很高,对世界健康构成严重威胁。为了最大限度地为患者提供护理并指导临床决策,了解治疗结果和存活率非常重要:这项回顾性研究评估了2010年至2022年间在一家三级医疗机构接受治疗的OSCC患者的治疗结果和生存率。数据包括人口统计学数据、肿瘤特征、治疗方案和随访结果。统计分析评估了治疗方法与生存率之间的关系:共有 107 名 OSCC 患者。与放疗和化疗相比,手术作为最常见的治疗方法,复发率更低,总生存率更高。不同治疗方案的生存率存在显著差异(P < 0.05):结论:手术治疗是主流。结论:手术是主要手段,而辅助治疗是疾病治疗的补充。本研究强调了根据患者的独特属性和肿瘤特征制定个性化治疗策略的重要性,以最大限度地提高 OSCC 患者的治疗效果。为了证实这些结果并研究最前沿的治疗方法,有必要进行更多的调查。
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