Rhabdomyolysis Induced by Levetiracetam: A Case Report in Kuwait.

IF 0.9 Q4 CLINICAL NEUROLOGY Case Reports in Neurological Medicine Pub Date : 2024-09-21 eCollection Date: 2024-01-01 DOI:10.1155/2024/1234738
Moaz Qureshi, Prakash A Abraham, Abdullah Al-Faras, Omar M Bamasood, Kamal M Matar
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Abstract

Epilepsy is a common disorder caused by a myriad of drugs, of that levetiracetam is being commonly used late because of its strong safety profile and efficacy. With the increasing usage of drugs, some rare side effects may sometimes appear that can escape the most stringent checks, possibly due to the rarity of their occurrence. Rhabdomyolysis is known to occur in some patients owing to a variety of causes, even leading to kidney injury. When a drug has a side effect that is not well recognized in the literature, especially when the side effect can mimic an adverse effect of an uncommon primary illness, identifying the causal factor can be doubly difficult. To date, only limited studies have been published suggesting rhabdomyolysis linked to levetiracetam use. We report the first case of levetiracetam-induced rhabdomyolysis in Kuwait.

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左乙拉西坦诱发横纹肌溶解症:科威特病例报告。
癫痫是一种常见疾病,由无数种药物引起,其中左乙拉西坦因其强大的安全性和疗效而被广泛使用。随着药物使用量的增加,有时可能会出现一些罕见的副作用,但可能由于其发生的罕见性,这些副作用可以逃过最严格的检查。众所周知,横纹肌溶解症会因各种原因发生在一些患者身上,甚至导致肾脏损伤。当一种药物的副作用在文献中没有得到很好的确认时,尤其是当这种副作用可以模拟一种不常见的原发性疾病的不良反应时,确定致病因素就会加倍困难。迄今为止,只有有限的研究表明横纹肌溶解症与左乙拉西坦的使用有关。我们报告了科威特首例由左乙拉西坦诱发的横纹肌溶解症病例。
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审稿时长
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