Acute Disseminated Encephalomyelitis Presenting with Neuropsychiatric Symptoms.

IF 0.7 Q4 PEDIATRICS Case Reports in Pediatrics Pub Date : 2024-09-17 eCollection Date: 2024-01-01 DOI:10.1155/2024/9810844
Mrinal Shrestha, Anish Joshi, Ajit Pandey, Aashutosh Chaudhary, Aman Raj Shrestha, Naman Koju, Sujan Timilsina, Ashlesha Chaudhary
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Abstract

Background: Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated pathology involving inflammatory demyelination of the central nervous system. Case Presentation. In this case report, we present the case of a nine-year-old female who exhibited altered mental status and focal neurological deficit, subsequently diagnosed as ADEM based on clinical presentation and magnetic resonance imaging (MRI) findings. The patient was managed symptomatically along with glucocorticoids.

Conclusion: ADEM must be suspected when a patient, especially a child, presents with prodromal symptoms followed by multifocal neurological symptoms. Diagnosis can be established with an MRI brain scan. Most patients respond to high-dose intravenous glucocorticoids.

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出现神经精神症状的急性播散性脑脊髓炎。
背景:急性播散性脑脊髓炎(ADEM急性播散性脑脊髓炎(ADEM)是一种罕见的免疫介导病理,涉及中枢神经系统的炎性脱髓鞘。病例介绍。在本病例报告中,我们介绍了一名九岁女性的病例,她表现出精神状态改变和局灶性神经功能缺损,随后根据临床表现和磁共振成像(MRI)结果被诊断为 ADEM。患者接受了对症治疗和糖皮质激素治疗:结论:当患者(尤其是儿童)出现前驱症状,继而出现多灶性神经症状时,必须怀疑 ADEM。核磁共振脑部扫描可确定诊断。大多数患者对大剂量静脉注射糖皮质激素有反应。
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来源期刊
自引率
11.10%
发文量
48
审稿时长
13 weeks
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