Cochlear Synaptopathy Evaluation With Electrocochleography in Patients With Hearing Difficulty in Noise Despite Normal Hearing Levels

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY Clinical Otolaryngology Pub Date : 2024-09-30 DOI:10.1111/coa.14235

Murat Yaşar, Fatih Öner, Fatma Atalay, Sezai Sacid Anbar

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Abstract

Objective

This study examined patients with normal hearing thresholds who had trouble understanding speech in noise. We used electrocochleography (ECochG) to detect and compare SP/AP amplitude area ratios, a potential indicator of cochlear synaptopathy, and investigate speech perception disorder in noise.

Methods

The study included 68 people aged between 18 and 65 years, 35 patients and 33 healthy volunteers, who applied to the otorhinolaryngology clinic between November 2023 and March 2024 with a 2-month history of difficulty understanding speech in noisy environments. Everyone was given a tiptrode electrode ECochG test, and the results were compared between groups. An ECochG test was recorded with tiptrode electrodes and was performed on all participants, and the results were compared between groups.

Results

In the ECochG test, the summation potential/action potential (SP/AP) amplitude and area ratios of patients who had difficulty understanding speech in a noisy environment were statistically higher than those of the control group.

Conclusion

ECochG testing may provide additional evidence to evaluate auditory nerve pathways.

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用电耳蜗造影术评估听力水平正常但在噪音中听力困难的患者的耳蜗突触病。

研究目的本研究对听阈正常但在噪声中理解言语有困难的患者进行了调查。我们使用耳蜗电图（ECochG）检测和比较 SP/AP 振幅面积比（耳蜗突触病的潜在指标），并研究噪声中的言语感知障碍：研究对象包括 68 名年龄在 18 岁至 65 岁之间的人，其中 35 名是患者，33 名是健康志愿者，他们于 2023 年 11 月至 2024 年 3 月期间到耳鼻喉科门诊就诊，有 2 个月的嘈杂环境中言语理解困难病史。每个人都接受了尖端电极心电图测试，并对各组结果进行了比较。用尖端电极记录所有参与者的心电图测试，并比较各组之间的结果：结果：在心电图测试中，在嘈杂环境中理解语言有困难的患者的总和电位/动作电位（SP/AP）振幅和面积比在统计学上高于对照组：结论：心电图测试可为评估听觉神经通路提供更多证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Otolaryngology 医学-耳鼻喉科学

CiteScore

4.00

自引率

4.80%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.