Descripción de un caso: liposarcoma de mama radioinducido

Abstract

Main symptoms and/or clinical findings

Breast sarcoma is a very rare entity that constitutes only 1% of all primary malignant breast tumors. It has a very poor prognosis with a high risk of recurrence. In this article, we present the case of a patient diagnosed with breast liposarcoma after having received radiotherapy for a previous breast carcinoma.

Main diagnoses

Due to the rarity of breast liposarcoma, it is important to make an adequate differential diagnosis. In our case, the study of overexpression of the MDM2 and/or CDK4 proteins allowed us to establish the definitive diagnosis.

Therapeutic interventions and results

The patient in our case underwent surgery, obtaining tumor-free margins with a favorable subsequent evolution. She currently has 18 months of disease-free survival.

Conclusion

The treatment of breast liposarcoma is mainly surgical since this sarcoma has a poor response to both chemotherapy and radiotherapy. The correct tumor resection is the most important prognostic factor for local control of the disease and long-term survival.