Behcet's disease-related panuveitis following COVID-19 vaccination: A case report.

IF 1.4 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING World journal of radiology Pub Date : 2024-09-28 DOI:10.4329/wjr.v16.i9.460

Rou-Ting Lin, Pei-Kang Liu, Chia-Wei Chang, Kai-Chun Cheng, Kuo-Jen Chen, Yo-Chen Chang

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Abstract

Background: Behcet's disease (BD) is an inflammatory disorder known for various symptoms, including oral and genital ulcers and ocular inflammation. Panuveitis, a severe eye condition, is rare as the first sign of BD.

Case summary: We present an unusual case of a 30-year-old man who developed panuveitis after receiving the mRNA-based coronavirus disease 2019 (COVID-19) vaccine (Moderna). Laboratory tests ruled out infections, but he had a positive HLA-B51 result and a history of genital ulcer and oral ulcers, leading to a BD diagnosis. Treatment with corticosteroids improved his condition. Interestingly, he had another episode of panuveitis after the second mRNA vaccine dose, which also responded to corticosteroids.

Conclusion: This case highlights the rare onset of BD following mRNA COVID-19 vaccination, suggesting a potential link between these vaccines and BD's eye symptoms, emphasizing the importance of quick treatment in similar cases.

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接种 COVID-19 疫苗后引发的与白塞氏病相关的泛葡萄膜炎：病例报告。

背景：白塞氏病（BD）是一种炎症性疾病，有多种症状，包括口腔和生殖器溃疡以及眼部炎症。病例摘要：我们报告了一例不寻常的病例，一名 30 岁的男子在接种了基于 mRNA 的冠状病毒病 2019（COVID-19）疫苗（Moderna）后出现了泛发性葡萄膜炎。实验室检查排除了感染的可能性，但他的 HLA-B51 结果呈阳性，且有生殖器溃疡和口腔溃疡病史，因此被诊断为 BD。皮质类固醇治疗改善了他的病情。有趣的是，他在接种第二剂 mRNA 疫苗后再次发生泛葡萄膜炎，皮质类固醇治疗也起效：本病例突显了接种mRNA COVID-19疫苗后出现BD的罕见情况，表明这些疫苗与BD的眼部症状之间存在潜在联系，并强调了在类似病例中快速治疗的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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World journal of radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

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