[Pediatric soft tissue tumors : Tumors of uncertain origin].

Pathologie (Heidelberg, Germany) Pub Date : 2024-11-01 Epub Date: 2024-10-02 DOI:10.1007/s00292-024-01356-z
K Greimelmaier, C Vokuhl
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Abstract

Soft tissue tumors of childhood are an extremely heterogeneous group of tumors that require precise diagnosis for therapy. In this article, selected tumors of uncertain origin that exhibit characteristic histological, immunophenotypical, and molecular features are addressed. Angiomatoid fibrous histiocytoma, alveolar soft part sarcoma, extrarenal rhabdoid tumor, synovial sarcoma, and desmoplastic small round cell tumor differ in their pathology, their clinical behavior, and prognosis.

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[小儿软组织肿瘤:来源不明的肿瘤]。
儿童软组织肿瘤是一类异质性极强的肿瘤,需要精确诊断才能进行治疗。本文选取了一些在组织学、免疫表型和分子特征方面表现出特征性的起源不确定的肿瘤。血管瘤样纤维组织细胞瘤、肺泡软组织肉瘤、肾外横纹肌瘤、滑膜肉瘤和脱鳞小圆形细胞瘤在病理、临床表现和预后方面各不相同。
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