The relationship between aflatoxin M1 and immunoglobulin levels in cows' colostrum.

IF 2.6 4区医学 Q2 MYCOLOGY Mycotoxin Research Pub Date : 2024-10-03 DOI:10.1007/s12550-024-00565-y

Necdet Mutlu, Güler Yenice

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Abstract

The purpose of the present research was to assess the amounts of aflatoxin M1 (AFM₁) and immunoglobulin (IgA, IgG, and IgM) in cow colostrum samples, as well as their relationship. The sampling involved 90 cows (54 Montofon and 36 Simmental) from 15 independent farms. An appropriate number of samples from the total mixed ration (TMR) used in feeding the cows were collected simultaneously with the colostrum samples. AFB₁ in feed, AFM₁, and immunoglobulin (IgA, IgG, and IgM) levels in colostrum were evaluated using the ELISA method. The AFM₁ level in colostrum samples exceeded the maximum allowed values for raw milk. Ig levels were higher in Montofon-breed cows' colostrum than in Simmentals. However, it was determined that neither the breed nor the lactation number significantly affected the colostrum Ig level. It was determined that there was no linear relationship between the number of lactations and immunoglobulin levels or between AFM₁ and immunoglobulin levels in colostrum. Similarly, it was determined that there was no linear relationship between the AFB₁ level in the feed and the AFM₁ level in the colostrum of animals consuming these feeds.

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黄曲霉毒素 M1 与奶牛初乳中免疫球蛋白水平之间的关系。

本研究旨在评估奶牛初乳样本中黄曲霉毒素 M1（AFM1）和免疫球蛋白（IgA、IgG 和 IgM）的含量及其关系。采样涉及来自 15 个独立牧场的 90 头奶牛（54 头蒙托邦牛和 36 头西门塔尔牛）。在采集牛初乳样本的同时，还从饲喂奶牛的全混合日粮（TMR）中采集了适当数量的样本。使用 ELISA 方法评估饲料中的 AFB1、AFM1 和初乳中的免疫球蛋白（IgA、IgG 和 IgM）水平。初乳样本中的 AFM1 含量超过了生乳的最大允许值。蒙托邦品种奶牛初乳中的 Ig 含量高于西门塔尔牛。不过，经测定，品种和泌乳数对初乳 Ig 含量都没有显著影响。经测定，泌乳次数与免疫球蛋白水平之间或初乳中的 AFM1 与免疫球蛋白水平之间没有线性关系。同样，饲料中的 AFB1 含量与食用这些饲料的动物初乳中的 AFM1 含量之间也没有线性关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mycotoxin Research MYCOLOGYTOXICOLOGY-TOXICOLOGY

CiteScore

6.40

自引率

6.70%

发文量

期刊介绍： Mycotoxin Research, the official publication of the Society for Mycotoxin Research, is a peer-reviewed, scientific journal dealing with all aspects related to toxic fungal metabolites. The journal publishes original research articles and reviews in all areas dealing with mycotoxins. As an interdisciplinary platform, Mycotoxin Research welcomes submission of scientific contributions in the following research fields: - Ecology and genetics of mycotoxin formation - Mode of action of mycotoxins, metabolism and toxicology - Agricultural production and mycotoxins - Human and animal health aspects, including exposure studies and risk assessment - Food and feed safety, including occurrence, prevention, regulatory aspects, and control of mycotoxins - Environmental safety and technology-related aspects of mycotoxins - Chemistry, synthesis and analysis.