Diagnostic and therapeutic challenges in PD-associated non-motor symptoms: the roles of neurologists and consultant physicians.

IF 3.2 4区 医学 Q2 CLINICAL NEUROLOGY Journal of Neural Transmission Pub Date : 2024-10-01 Epub Date: 2024-10-07 DOI:10.1007/s00702-024-02838-3
C W Ip, J Kassubek, A Storch, L Tönges, M Wolz, W H Jost
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Abstract

In addition to their motor symptoms, almost all Parkinson's disease patients report non-motor symptoms (NMS) and, in the later course of the disease, non-motor fluctuations as well. These NMS encompass e.g. neuropsychiatric, gastrointestinal, urogenital, cardiovascular symptoms and pain. For a long time, these symptoms received no or at best very little attention, but there is a growing trend towards their recognition and treatment. Despite this progress, significant gaps remain, particularly due to the sometimes-limited expertise among neurologists regarding these symptoms. The clinical need to consequently treat these NMS raises the question of whether Movement Disorder specialists should and can address them sufficiently or if additional consultant physicians have to be enrolled. Therefore, our objective is to establish benchmarking criteria to outline a potential way forward. Ideally, Movement Disorder specialists should take on greater responsibility when treating non-motor PD symptoms, integrating diagnostic and therapeutic pathways from other medical disciplines where feasible.

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帕金森病相关非运动症状的诊断和治疗难题:神经科医生和顾问医生的作用。
除了运动症状外,几乎所有帕金森病患者都会出现非运动症状(NMS),在疾病后期还会出现非运动波动。这些非运动症状包括神经精神、胃肠道、泌尿生殖、心血管症状和疼痛等。长期以来,这些症状没有受到关注,或最多只受到极少关注,但现在有越来越多的人开始认识和治疗这些症状。尽管取得了这一进展,但仍然存在很大差距,特别是由于神经科医生对这些症状的专业知识有时很有限。因此,治疗这些 NMS 的临床需求提出了这样一个问题:运动障碍专科医生是否应该并能够充分解决这些问题,或者是否需要招募更多的顾问医生。因此,我们的目标是建立基准标准,勾勒出可能的前进方向。理想情况下,运动障碍专科医生在治疗帕金森病非运动症状时应承担更大的责任,并在可行的情况下整合其他医学学科的诊断和治疗途径。
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来源期刊
Journal of Neural Transmission
Journal of Neural Transmission 医学-临床神经学
CiteScore
7.20
自引率
3.00%
发文量
112
审稿时长
2 months
期刊介绍: The investigation of basic mechanisms involved in the pathogenesis of neurological and psychiatric disorders has undoubtedly deepened our knowledge of these types of disorders. The impact of basic neurosciences on the understanding of the pathophysiology of the brain will further increase due to important developments such as the emergence of more specific psychoactive compounds and new technologies. The Journal of Neural Transmission aims to establish an interface between basic sciences and clinical neurology and psychiatry. It intends to put a special emphasis on translational publications of the newest developments in the field from all disciplines of the neural sciences that relate to a better understanding and treatment of neurological and psychiatric disorders.
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