Oral Chronic Graft-versus-Host Disease and Oral Health after Allogeneic Hematopoietic Cell Transplantation — What the Care Team Needs to Know

IF 4.4 3区 医学 Q2 HEMATOLOGY Transplantation and Cellular Therapy Pub Date : 2024-09-01 Epub Date: 2024-10-05 DOI:10.1016/j.jtct.2024.07.006
Alexa M.G.A. Laheij , Eduardo Rodrigues Fregnani , Leandro Dorigan de Macedo , Nathaniel S. Treister
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Abstract

Oral chronic graft-versus-host disease (cGVHD) can present with a multitude of clinical signs and is associated with morbidity and lower quality of life. Oral cGVHC may affect the oral mucosa (reticular white striae, erythema, and/or ulcerations), the salivary glands (hyposalivation and/or xerostomia) and the peri-oral soft tissues (fibrosis and trismus). This review provides a practical and concise approach to the diagnosis and management of oral health needs in pediatric and adult alloHCT recipients within the first 2 years post-transplantation.
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同种异体造血细胞移植后的口腔慢性移植物抗宿主疾病和口腔健康--护理团队须知。
口腔慢性移植物抗宿主病(cGVHD)可表现出多种临床症状,与发病率和生活质量下降有关。口腔慢性移植物抗宿主疾病可能会影响口腔粘膜(网状白纹、红斑和/或溃疡)、唾液腺(唾液分泌减少和/或口腔干燥症)和口周软组织(纤维化和践踏)。本综述以实用、简明的方法介绍了儿童和成人异体器官移植受者在移植后头两年内口腔健康需求的诊断和管理。
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来源期刊
CiteScore
7.00
自引率
15.60%
发文量
1061
审稿时长
51 days
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