Eric Michel Charlemagne Junior Kessi, Kaoutar Maslouhi, Yousra Guelzim, Lina Belkouchi, Nazik Allali, Latifa Chat, Siham El Haddad
{"title":"Severe Hemophilic Arthropathy of the Knee: MRI Has Its Place.","authors":"Eric Michel Charlemagne Junior Kessi, Kaoutar Maslouhi, Yousra Guelzim, Lina Belkouchi, Nazik Allali, Latifa Chat, Siham El Haddad","doi":"10.1177/2333794X241280116","DOIUrl":null,"url":null,"abstract":"<p><p>Hemophilia is a congenital coagulopathy characterized by a deficiency of coagulation factors and the development of haematomas and haemarthrosis, either spontaneously or after minor trauma. Recurrent joint hemorrhage in hemophilia patients leads to progressive and degenerative arthropathy, which affects around 90% of patients with severe disease and contributes significantly to disease morbidity. Positive diagnosis is based on biology. Imaging, particularly MRI, plays an essential role in assessing the evolution and complications, especially osteoarticular complications. We report 2 cases of severe hemophilia A, who presented with almost identical clinical and radiological symptoms. The patients developed severe arthropathy with a course marked by recurrences of haemarthrosis.</p>","PeriodicalId":12576,"journal":{"name":"Global Pediatric Health","volume":"11 ","pages":"2333794X241280116"},"PeriodicalIF":1.4000,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11459556/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global Pediatric Health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/2333794X241280116","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Hemophilia is a congenital coagulopathy characterized by a deficiency of coagulation factors and the development of haematomas and haemarthrosis, either spontaneously or after minor trauma. Recurrent joint hemorrhage in hemophilia patients leads to progressive and degenerative arthropathy, which affects around 90% of patients with severe disease and contributes significantly to disease morbidity. Positive diagnosis is based on biology. Imaging, particularly MRI, plays an essential role in assessing the evolution and complications, especially osteoarticular complications. We report 2 cases of severe hemophilia A, who presented with almost identical clinical and radiological symptoms. The patients developed severe arthropathy with a course marked by recurrences of haemarthrosis.
血友病是一种先天性凝血病,其特点是缺乏凝血因子,自发或在轻微外伤后出现血肿和血性关节病。血友病患者反复出现的关节出血会导致进行性和退行性关节病,约 90% 的重症患者都会受到这种病的影响,并大大增加了疾病的发病率。阳性诊断以生物学为基础。影像学,尤其是核磁共振成像,在评估病情发展和并发症,特别是骨关节并发症方面发挥着至关重要的作用。我们报告了两例严重的 A 型血友病患者,他们的临床和影像学症状几乎完全相同。这两名患者都出现了严重的关节病,病程以血性关节炎复发为特征。