A Rare Complication of Cannabinoid Hyperemesis Syndrome.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-08 DOI:10.12659/AJCR.945106
Hallie E Knight, Abhinav Singla, Michael Smerina, Melissa P Cortes, Tatjana Gavrancic, Deborah A Baumgarten, Adrian G Dumitrascu, Ricardo J Pagan, Aleksandra Murawska Baptista
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Abstract

BACKGROUND Cognitive errors are common in medical practice and can have serious consequences for patients related to misdiagnosis and delays in diagnosis and treatment. We report a case in which cognitive error substantially influenced a patient's diagnosis and treatment. CASE REPORT This report recounts the case of an adolescent girl with symptoms similar to those of her previous episodes of tetrahydrocannabinol-induced hyperemesis, despite a 21-kg weight loss over 6 months. She sought care at multiple facilities until finally being diagnosed with superior mesenteric artery syndrome. Treatment was conservative with intravenous hydration, nasogastric feeding, and gastric decompression until duodenal compression was relieved. The patient's condition had improved at 7-month follow-up, and she declined surgical consultation. CONCLUSIONS This case report seeks to raise awareness of the effects of cognitive errors in clinical practice. This tendency to prematurely attribute symptoms to a known diagnosis and thereby overlook alternative and potentially more accurate explanations can lead to delays in diagnoses and treatments. Awareness of cognitive error is especially important in the context of the increasing prevalence of legalization of tetrahydrocannabinol/marijuana in several states. Superior mesenteric artery syndrome, although rare, is linked to high morbidity and mortality when the diagnosis is delayed; thus, it is crucial to consider it in the differential diagnosis for a patient with weight loss and abdominal pain. By sharing this case, we hope clinicians and patients can become more aware of this rare consequence of tetrahydrocannabinol use to facilitate more comprehensive patient-centered investigations.

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一种罕见的大麻催吐综合征并发症。
背景认知错误在医疗实践中很常见,会给患者带来误诊、延误诊断和治疗等严重后果。我们报告了一例认知错误严重影响患者诊断和治疗的病例。病例报告 本报告叙述了一个青春期女孩的病例,尽管她的体重在 6 个月内下降了 21 千克,但她的症状与之前发作的四氢大麻酚诱发的剧吐相似。她曾在多家医院就诊,最终被诊断为肠系膜上动脉综合征。保守治疗包括静脉补液、鼻饲和胃减压,直到十二指肠压迫症状缓解。随访 7 个月后,患者病情有所好转,但她拒绝接受手术治疗。结论 本病例报告旨在提高人们对临床实践中认知错误的影响的认识。过早地将症状归因于已知的诊断,从而忽略了其他可能更准确的解释,这种倾向会导致诊断和治疗的延误。在一些州四氢大麻酚/大麻合法化日益盛行的背景下,对认知错误的认识尤为重要。肠系膜上动脉综合征虽然罕见,但如果延误诊断,则会导致高发病率和高死亡率;因此,在对体重减轻和腹痛患者进行鉴别诊断时,必须考虑到肠系膜上动脉综合征。通过分享这个病例,我们希望临床医生和患者能更多地了解使用四氢大麻酚所导致的这种罕见后果,从而促进以患者为中心的更全面的检查。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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