Molecularly imprinted polymers-based biosensors for gynecological diagnostics and monitoring

IF 4.1 Q1 CHEMISTRY, ANALYTICAL Talanta Open Pub Date : 2024-09-28 DOI:10.1016/j.talo.2024.100364
Faezeh Ghorbanizamani , Hichem Moulahoum , Figen Zihnioglu , Suna Timur
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Abstract

Molecularly Imprinted Polymers (MIPs) offer promising advancements in gynecological diagnostics due to their high selectivity, stability, and cost-effectiveness. This review explores the application of MIP-based biosensors in detecting biomarkers for gynecological cancer, infections, and hormonal monitoring. Despite significant progress in MIP technology, its integration into clinical gynecology remains limited. The review provides a deep dive into the synthesis and characterization process of MIPs, current diagnostic methods, and the potential of emerging diagnostic approaches such as microfluidics and nanotechnology. Then, an overview of the various conditions, diseases, and potential biomarkers is explored. Emphasizing the importance of women's health, the review analyzes the latest research in MIP-based biosensing of gynecological conditions and calls for increased research and development to bridge the gap between laboratory innovation and clinical application. The goal is to enhance early detection, improve patient outcomes, and reduce healthcare costs. This advancement is essential for better disease management and personalized treatment in gynecology.

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基于分子印迹聚合物的妇科诊断和监测生物传感器
分子印迹聚合物(MIP)具有高选择性、稳定性和成本效益,有望推动妇科诊断技术的发展。本综述探讨了基于 MIP 的生物传感器在检测妇科癌症、感染和激素监测生物标记物方面的应用。尽管 MIP 技术取得了重大进展,但其在妇科临床中的应用仍然有限。本综述深入探讨了 MIP 的合成和表征过程、当前的诊断方法以及微流控和纳米技术等新兴诊断方法的潜力。然后,概述了各种情况、疾病和潜在的生物标记物。该综述强调了妇女健康的重要性,分析了基于 MIP 的妇科疾病生物传感的最新研究,呼吁加强研发,缩小实验室创新与临床应用之间的差距。我们的目标是加强早期检测,改善患者预后,降低医疗成本。这一进步对于妇科疾病的更好管理和个性化治疗至关重要。
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来源期刊
Talanta Open
Talanta Open Chemistry-Analytical Chemistry
CiteScore
5.20
自引率
0.00%
发文量
86
审稿时长
49 days
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