Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708)
K. Zwart , M.N.G.J.A. Braat , F.H. van der Baan , A.M. May , J.M.L. Roodhart , D. Al-Toma , J.M.M.B. Otten , M. Los , T. Oostergo , R.J.A. Fijneman , J.M. van Dodewaard-de Jong , C.J.A Punt , G. Meijer , J.J.W. Lagendijk , M. Koopman , M. Intven , G.M. Bol
{"title":"Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708)","authors":"K. Zwart , M.N.G.J.A. Braat , F.H. van der Baan , A.M. May , J.M.L. Roodhart , D. Al-Toma , J.M.M.B. Otten , M. Los , T. Oostergo , R.J.A. Fijneman , J.M. van Dodewaard-de Jong , C.J.A Punt , G. Meijer , J.J.W. Lagendijk , M. Koopman , M. Intven , G.M. Bol","doi":"10.1016/j.ctro.2024.100874","DOIUrl":null,"url":null,"abstract":"<div><div>Colorectal cancer patients with ≤10 unresectable metastases were treated with single-fraction sub-ablative radiotherapy in addition to standard of care systemic therapy in a single-arm, open-label, multicenter, pilot study (SIRIUS) to assess feasibility and safety. Results indicate that radiotherapy combined with systemic therapy is feasible and safe in this population.</div></div>","PeriodicalId":10342,"journal":{"name":"Clinical and Translational Radiation Oncology","volume":"49 ","pages":"Article 100874"},"PeriodicalIF":2.7000,"publicationDate":"2024-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Translational Radiation Oncology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405630824001514","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Colorectal cancer patients with ≤10 unresectable metastases were treated with single-fraction sub-ablative radiotherapy in addition to standard of care systemic therapy in a single-arm, open-label, multicenter, pilot study (SIRIUS) to assess feasibility and safety. Results indicate that radiotherapy combined with systemic therapy is feasible and safe in this population.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
