{"title":"Mn-Catalyzed Three-Component Coupling Reactions of Carboxylic Acids, Diazo Compounds, and Tertiary Amines for the Synthesis of β-Amino Esters","authors":"Rongxiang Chen, Xingshuo Li, Lanying Chen, Kai-Kai Wang, Changqing Miao","doi":"10.1002/aoc.7678","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>A simple and efficient three-component coupling reaction of carboxylic acids, diazo compounds, and tertiary amines catalyzed by manganese has been described. This reaction proceeds smoothly under mild conditions to afford various <i>β</i>-amino esters in moderate to good yields by using O<sub>2</sub> as the terminal oxidant. In this process, Mn-based carbene radical, single-electron transfer, and nucleophilic attack were fused into a reaction system.</p>\n </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"38 11","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Organometallic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/aoc.7678","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
A simple and efficient three-component coupling reaction of carboxylic acids, diazo compounds, and tertiary amines catalyzed by manganese has been described. This reaction proceeds smoothly under mild conditions to afford various β-amino esters in moderate to good yields by using O2 as the terminal oxidant. In this process, Mn-based carbene radical, single-electron transfer, and nucleophilic attack were fused into a reaction system.
期刊介绍：
All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.
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