Novel method for assessing sinusoidal obstruction syndrome using four-dimensional computed tomography

EJHaem Pub Date : 2024-07-31 DOI:10.1002/jha2.990

Saori Shimoyama-Ibuki, Satoshi Iyama, Yoshiya Ohashi, Kento Ono, Yusuke Sugama, Chisa Fujita, Akari Goto, Hiroto Horiguchi, Akihito Fujimi, Takeo Tanaka, Kohichi Takada, Koh-Ichi Sakata, Masayoshi Kobune

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Abstract

Introduction

To diagnose sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD), transabdominal ultrasonography is usually used to detect hemodynamic changes, but we tried to detect the changes using four-dimensional computed tomography (4D-CT). A 42-year-old Japanese woman was diagnosed with late-onset SOS/VOD with transabdominal ultrasonography and was also assessed using 4D-CT. Method We analyzed the portal vein (PV) contrast effect every 1.5 seconds and plotted the values of the contrast effect. With this graph, we analyzed three hemodynamic parameters.

Result

We found that these parameters correlated with the patient's status and indicated stasis due to sinusoid constriction.

Conclusion

4D-CT may become a helpful tool to diagnose and follow up with SOS/VOD.

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利用四维计算机断层扫描评估窦道阻塞综合征的新方法

导言：诊断窦道阻塞综合征/静脉闭塞性疾病（SOS/VOD）时，通常使用经腹超声波检查来检测血流动力学变化，但我们尝试使用四维计算机断层扫描（4D-CT）来检测这些变化。一名 42 岁的日本女性通过经腹超声波检查被诊断为晚发性 SOS/VOD，并使用四维计算机断层扫描进行了评估。方法我们每 1.5 秒分析一次门静脉（PV）对比度效果，并绘制对比度效果图。通过此图，我们分析了三个血液动力学参数。结果我们发现这些参数与患者的状态相关，并显示出由于窦状静脉收缩导致的瘀血。结论 4D-CT 可能成为诊断和随访 SOS/VOD 的有用工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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EJHaem

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