On role models and Joe LeDoux.

IF 2.9 2区 医学 Q2 NEUROSCIENCES Cerebral cortex Pub Date : 2024-10-17 DOI:10.1093/cercor/bhae417
Sheena A Josselyn
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Abstract

Joseph LeDoux is a pioneering neuroscientist who has made profound discoveries that continue to impact our understanding of the neural basis of emotion and memory, particularly the role of the amygdala in threat conditioning. LeDoux's trailblazing and elegant studies were some of the first to examine the circuit basis of behavior. His work combined techniques to trace pathways into and out of the amygdala important for threat conditioning and related behaviors. Since that time, these types of circuit tracing studies have exploded in popularity across neuroscience, and I would argue, we all owe a debt to LeDoux for this. LeDoux has made numerous additional contributions to neuroscience and, by bringing emotion back to neuroscience, has helped unite neuroscience with psychology. A gifted writer with a knack for communicating complicated scientific ideas in an accessible manner, LeDoux has become an ambassador of science who uses his love of music to help educate and inspire. Perhaps more important than these laudable scientific achievements, LeDoux is also a true "gentleman" of science, showing that science need not be a contact sport. Here, I give a personal account on why Joseph LeDoux is one of my scientific role models.

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关于榜样和乔-勒杜。
约瑟夫-勒杜 (Joseph LeDoux) 是一位开创性的神经科学家,他的深刻发现不断影响着我们对情绪和记忆神经基础的理解,尤其是杏仁核在威胁条件反射中的作用。勒杜开创性的优雅研究是最早研究行为回路基础的研究之一。他的研究结合各种技术,追踪了进出杏仁核的路径,这些路径对威胁调节和相关行为非常重要。从那时起,这类回路追踪研究在神经科学领域大受欢迎,我认为,我们都欠勒杜一笔债。勒杜为神经科学做出了许多额外的贡献,并通过将情感带回到神经科学中,帮助神经科学与心理学联合起来。勒杜是一位才华横溢的作家,善于用通俗易懂的方式传达复杂的科学思想,他已成为科学的使者,用自己对音乐的热爱来帮助教育和启发人们。也许比这些值得称赞的科学成就更重要的是,勒杜还是一位真正的科学 "绅士",他向人们展示了科学不一定是一项接触性运动。在这里,我将以个人身份讲述为什么约瑟夫-勒杜是我的科学楷模之一。
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来源期刊
Cerebral cortex
Cerebral cortex 医学-神经科学
CiteScore
6.30
自引率
8.10%
发文量
510
审稿时长
2 months
期刊介绍: Cerebral Cortex publishes papers on the development, organization, plasticity, and function of the cerebral cortex, including the hippocampus. Studies with clear relevance to the cerebral cortex, such as the thalamocortical relationship or cortico-subcortical interactions, are also included. The journal is multidisciplinary and covers the large variety of modern neurobiological and neuropsychological techniques, including anatomy, biochemistry, molecular neurobiology, electrophysiology, behavior, artificial intelligence, and theoretical modeling. In addition to research articles, special features such as brief reviews, book reviews, and commentaries are included.
期刊最新文献
Individual differences in functional connectivity during suppression of imagined threat. When emotion and time meet from human and rodent perspectives: a central role for the amygdala? Introspective psychophysics for the study of subjective experience. Examining threat responses through a developmental lens. Causal relationship between cortical structural changes and onset of anxiety disorder: evidence from Mendelian randomization.
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