Effectiveness and safety of the modified multiple mode procedures versus traditional multiple mode procedures on treating facial atrophic acne scars: a propensity score matching retrospective cohort study.

IF 2.1 4区 医学 Q3 ENGINEERING, BIOMEDICAL Lasers in Medical Science Pub Date : 2024-10-19 DOI:10.1007/s10103-024-04211-y
Ziwei Ding, Zhonglan Pan, Yanqiu Tang, Sihui Wang, Hui Hua, Zuoqiong Hou, Bingrong Zhou
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Abstract

Multiple mode procedures (MMP) of fractional CO2 laser provide higher efficacy and shorter downtime in treating acne scars, compared to traditional fractional CO2 laser therapy. This study aims to evaluate the effectiveness and safety of modified MMP integrated with fractional microneedle radiofrequency (FMR), ultra-pulse CO2 laser and fractional CO2 laser in treating acne scars. A retrospective analysis of 162 acne scar patients treated with MMP or modified MMP was conducted. Acne scars were evaluated using the Echelle d'Evaluation Clinique des Cicatrices d'Acné (ECCA) grading scale, modified Manchester Scar Scale (mMSS), and Global Assessment Scale (GAS). Baseline variables were balanced with propensity score matching (PSM) to improve the comparability of treatment effectiveness and safety between groups. Among 162 patients with facial acne scars, 68 were treated with modified MMP and 94 with traditional MMP. After PSM, both groups had 55 patients with comparable baseline characteristics (P > 0.05). The ECCA score decreased more significantly in the modified MMP group (60%±11%) than in the MMP group (45%±16.6%, P < 0.001). The modified MMP group also had higher mMSS color score (2.6 ± 0.7 vs. 2.1 ± 0.9, P = 0.005), greater reduction in pore size and skin laxity (P < 0.001), shorter postoperative erythema duration (22.2 ± 4.0 vs. 31.3 ± 3.7 days, P < 0.001), but higher pain scores (Visual Analogue Scale, VAS: 6.7 ± 1.6 vs. 3.8 ± 0.8, P < 0.001). Modified MMP is more effective than traditional MMP in treating acne scars, especially for patients with large pores and skin laxity.

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改良多模式手术与传统多模式手术治疗面部萎缩性痤疮疤痕的有效性和安全性:倾向得分匹配回顾性队列研究。
与传统的二氧化碳点阵激光疗法相比,二氧化碳点阵激光的多模式疗法(MMP)治疗痤疮疤痕的疗效更高,停工期更短。本研究旨在评估改良MMP与点阵微针射频(FMR)、超脉冲二氧化碳激光和点阵二氧化碳激光综合治疗痤疮疤痕的有效性和安全性。对162名接受MMP或改良MMP治疗的痤疮疤痕患者进行了回顾性分析。痤疮疤痕采用临床痤疮评分表(ECCA)、改良曼彻斯特疤痕量表(mMSS)和全球评估量表(GAS)进行评估。通过倾向得分匹配法(PSM)对基线变量进行了平衡,以提高各组间治疗效果和安全性的可比性。在162名面部痤疮疤痕患者中,68人接受了改良MMP治疗,94人接受了传统MMP治疗。PSM 后,两组患者的基线特征相当,均为 55 例(P > 0.05)。改良 MMP 组(60%±11%)的 ECCA 评分比 MMP 组(45%±16.6%,P
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来源期刊
Lasers in Medical Science
Lasers in Medical Science 医学-工程:生物医学
CiteScore
4.50
自引率
4.80%
发文量
192
审稿时长
3-8 weeks
期刊介绍: Lasers in Medical Science (LIMS) has established itself as the leading international journal in the rapidly expanding field of medical and dental applications of lasers and light. It provides a forum for the publication of papers on the technical, experimental, and clinical aspects of the use of medical lasers, including lasers in surgery, endoscopy, angioplasty, hyperthermia of tumors, and photodynamic therapy. In addition to medical laser applications, LIMS presents high-quality manuscripts on a wide range of dental topics, including aesthetic dentistry, endodontics, orthodontics, and prosthodontics. The journal publishes articles on the medical and dental applications of novel laser technologies, light delivery systems, sensors to monitor laser effects, basic laser-tissue interactions, and the modeling of laser-tissue interactions. Beyond laser applications, LIMS features articles relating to the use of non-laser light-tissue interactions.
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