[Combined use of biomaterials and revascularisation in autoplasty of ulnar nerve].

A G Fedyakov, O N Dreval, A V Gorozhanin, D N Grekov, L A Sidneva, Z Kh Plieva, M A Razin, G N Chapandze
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Abstract

Surgical treatment of peripheral nerve injuries is effective in only 50% of cases. This is primarily due to the significant extent of the diastasis between the fragments of the damaged nerve, in which autoplasty has to be performed. The drawbacks of this technique are the formation of scar tissue, possible necrotisation of the autograft, mismatch of the donor and recipient nerve diameters. In order to overcome these drawbacks and improve the efficiency of surgical intervention, the study presents a clinical case of successful multifascicular ulnar nerve autoplasty with the use of domestic biodegradable biomaterials SpheroGel and ElastoPob, revascularization of the autograft with a connective tissue flap on a vascular pedicle. A persistent regression of local pain syndrome was observed in the early postoperative period. The effectiveness of the performed surgical intervention was confirmed by ultrasound examination: there was no evidence of neuroma in the area of the operation, regeneration of nerve bundles was noted at the site of stitching. Positive dynamics was observed in the results of VAS, DN4, DASH questionnaires.

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[在尺神经自体成形术中联合使用生物材料和血管再造]。
外周神经损伤的手术治疗仅在 50%的病例中有效。这主要是由于受损神经片段之间的吻合范围很大,必须进行自体移植。这种技术的缺点是会形成疤痕组织,自体移植可能会坏死,供体和受体神经直径不匹配。为了克服这些缺点,提高手术干预的效率,本研究介绍了一例使用国产可降解生物材料 SpheroGel 和 ElastoPob 成功进行多筋膜尺神经自体移植术的临床病例,并在血管蒂上用结缔组织瓣对自体移植物进行血管再造。术后早期,局部疼痛综合征持续缓解。超声波检查证实了手术干预的有效性:手术区域没有神经瘤的迹象,缝合部位有神经束再生。VAS、DN4、DASH 问卷调查结果显示了积极的动态变化。
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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
75
期刊介绍: Scientific and practical peer-reviewed journal. This publication covers the theoretical, practical and organizational problems of modern neurosurgery, the latest advances in the treatment of various diseases of the central and peripheral nervous system. Founded in 1937. English version of the journal translates from Russian version since #1/2013.
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