Extensive metastatic ependymoma with long-term progression-free survival with capecitabine plus temozolomide combination chemotherapy: A case report.

Engin Hendem, Mustafa Korkmaz, Murat Araz, Melek K Eryılmaz, Dilek Çağlayan, Seda T Ayçiçek, Buğra Kaya, Mehmet Artaç
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Abstract

Abstract: We wanted to present a rare case of metastatic grade 2 spinal ependymoma with an atypical course at the time of diagnosis. Temozolomide plus capecitabine chemotherapy was started in May 2018 on a 30-year-old female patient with sacral ependymoma who had extensive lung metastases at the time of diagnosis. The patient remained in remission for approximately 29 months, and the current chemotherapy was continued until it progressed in November 2020. According to this case report, a combination of temozolomide and capecitabine may be the best treatment option for ependymoma patients.

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卡培他滨加替莫唑胺联合化疗后,广泛转移性癫痫瘤获得长期无进展生存:病例报告。
摘要:我们想介绍一例罕见的转移性2级脊柱外胚瘤病例,确诊时病程不典型。2018年5月,一名30岁的女性骶骨上皮瘤患者开始接受替莫唑胺加卡培他滨化疗,该患者在确诊时已有广泛的肺转移。该患者的病情持续缓解了约 29 个月,目前的化疗一直持续到 2020 年 11 月病情进展。根据这份病例报告,替莫唑胺和卡培他滨联合用药可能是脑外胚瘤患者的最佳治疗方案。
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