Manganese(iii) acetate in organic synthesis: a review of the past decade

Abstract

Mn(OAc)₃ has emerged as a highly valuable one-electron oxidant in the fields of synthetic and medicinal chemistry, owing to its mild reactivity, economic feasibility, and low toxicity. In recent years, significant advancements have been made in Mn(OAc)₃ chemistry, markedly expanding the boundaries of synthetic radical chemistry. This review offers a consolidated and critical overview of the latest developments and applications of Mn(OAc)₃ in organic synthesis over the past decade. The emphasis is placed on efforts that strive to achieve milder reaction conditions and broaden the range of synthesis opportunities. It is our intention that this review will serve as a valuable reference for the synthetic and medicinal chemistry communities, inspiring further exploration and innovation in this dynamic field.