Alveolar Ridge Regeneration With Open Versus Closed Healing in Damaged Extraction Sockets: A Preclinical In Vivo Study.

IF 4.8 1区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Clinical Oral Implants Research Pub Date : 2024-10-28 DOI:10.1111/clr.14376

Jae-Won Choi, Jin-Young Park, Jae-Kook Cha, Pham-Duong Hieu, Hwi-Dong Jung, Chang-Sung Kim

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Abstract

Objective: The objective of this study was to compare open versus closed healing of soft and hard tissue following alveolar ridge preservation (ARP) procedures in damaged extraction sockets.

Materials and methods: ARP was performed in five mongrel dogs using collagenated deproteinized bovine bone mineral (cDBBM) and a resorbable non-cross-linked collagen membrane (NCCM) in damaged extraction sockets, with each socket entrance left either open (open group) or closed (closed group). Clinical wound epithelization at the socket entrance and the dimensions of keratinized tissue were evaluated over time. Additionally, the augmented ridge dimensions and new bone formation were assessed radiographically and histologically at 8 weeks after surgery.

Results: The dimensions of the socket entrance gradually decreased in the open group, and wound epithelization was almost complete within 4 weeks. The mucogingival junction was maintained more apically in the open group than in the closed group (0.14 ± 0.40 mm vs. -0.86 ± 0.71 mm [mean ± SD], p < 0.05). The augmented ridge dimensions did not differ significantly between the open and closed groups (93.1% ± 5.4% vs. 88.3% ± 11.2%, p > 0.05). Histological analyses revealed no significant differences in the amount of newly formed bone. However, membrane resorption in the crestal region was more pronounced in the open group.

Conclusion: Open and closed healing approaches for ARP in extraction sockets with damaged buccal wall resulted in similar ridge dimensions and new bone formation. However, there was less reduction of the buccal bone crest and wider keratinized tissue width after open healing.

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受损拔牙基台开放式愈合与封闭式愈合的牙槽嵴再生：临床前体内研究。

研究目的本研究的目的是比较受损拔牙基台的牙槽嵴保留（ARP）术后软组织和硬组织的开放式愈合与封闭式愈合：使用胶原蛋白化牛骨矿（cDBBM）和可吸收的非交联胶原膜（NCCM）在受损的拔牙窝中对五只杂种狗进行了ARP治疗，每个窝的入口都是开放的（开放组）或封闭的（封闭组）。随着时间的推移，对牙槽骨入口处的临床伤口上皮化和角化组织的尺寸进行评估。此外，在术后 8 周，还对增大的牙脊尺寸和新骨形成进行了放射学和组织学评估：结果：开放组的牙槽窝入口尺寸逐渐缩小，伤口上皮化在 4 周内基本完成。与封闭组相比，开放组的粘龈交界处在顶端保持得更好（0.14 ± 0.40 mm vs. -0.86 ± 0.71 mm [平均值±标准差]，P 0.05）。组织学分析显示，新形成的骨量没有明显差异。然而，开放组骨嵴区域的骨膜吸收更为明显：结论：在颊侧壁受损的拔牙基台中采用开放式和封闭式ARP愈合方法可获得相似的牙脊尺寸和新骨形成。然而，开放式愈合后颊骨嵴的缩小程度较小，角化组织宽度较宽。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Oral Implants Research 医学-工程：生物医学

CiteScore

7.70

自引率

11.60%

发文量

149

审稿时长

3 months

期刊介绍： Clinical Oral Implants Research conveys scientific progress in the field of implant dentistry and its related areas to clinicians, teachers and researchers concerned with the application of this information for the benefit of patients in need of oral implants. The journal addresses itself to clinicians, general practitioners, periodontists, oral and maxillofacial surgeons and prosthodontists, as well as to teachers, academicians and scholars involved in the education of professionals and in the scientific promotion of the field of implant dentistry.