Cyanoacrylate versus Collagen Membrane as a Sealing for Alveolar Ridge Preservation: A Randomized Clinical Trial.

IF 5 3区医学 Q1 ENGINEERING, BIOMEDICAL Journal of Functional Biomaterials Pub Date : 2024-09-24 DOI:10.3390/jfb15100279

Fabio Camacho-Alonso, Osmundo Gilbel-Del Águila, Paula Ferrer-Díaz, David Peñarrocha-Oltra, Yolanda Guerrero-Sánchez, Juan Carlos Bernabeu-Mira

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Abstract

This study involved a randomized clinical trial that included 140 patients. Alveolar ridge preservation was performed with xenografts. Sealing in the control group consisted of a collagen membrane versus cyanoacrylate in the test group. The dental implants were placed immediately after extraction. The variables were evaluated at 3, 12, and 18 months of follow-up. Pearson's chi-squared test was used for qualitative variables and the Student t-test for related samples was used for quantitative variables. The change in buccolingual alveolar bone width was significantly greater in the CMX group than in the CX group after three months (p < 0.005). However, significance was not reached at the other follow-up timepoints (p > 0.005). CAL showed significantly greater values in the CMX group than in the CX group (p < 0.005), and MBL proved greater in the CMX group than in the CX group, with p < 0.001. Five membrane exposures were recorded in the CMX group. Cyanoacrylate as a sealing method for alveolar ridge preservation seems to afford better clinical and radiological results than collagen membrane.

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氰基丙烯酸酯与胶原蛋白膜作为牙槽嵴保留的密封方法：随机临床试验。

这项研究是一项随机临床试验，共有 140 名患者参与。牙槽嵴保存采用异种移植。对照组使用胶原膜进行密封，而试验组则使用氰基丙烯酸酯进行密封。牙科植入物在拔牙后立即植入。在 3 个月、12 个月和 18 个月的随访中对各变量进行了评估。定性变量采用皮尔逊卡方检验，定量变量采用相关样本的学生 t 检验。三个月后，CMX 组的颊舌侧牙槽骨宽度变化明显大于 CX 组（P < 0.005）。但是，在其他随访时间点上没有达到显著性（P > 0.005）。CMX 组的 CAL 值明显高于 CX 组（p < 0.005），CMX 组的 MBL 值高于 CX 组（p < 0.001）。CMX 组记录了五次膜暴露。与胶原膜相比，氰基丙烯酸酯作为牙槽嵴保存的密封方法似乎能提供更好的临床和放射学效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Functional Biomaterials Engineering-Biomedical Engineering

CiteScore

4.60

自引率

4.20%

发文量

226

审稿时长

11 weeks

期刊介绍： Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.