Club Drugs and Psychiatric Outcomes: A Descriptive Case Series from Spain.

IF 4.3 3区 医学 Q2 CHEMISTRY, MEDICINAL Pharmaceuticals Pub Date : 2024-10-17 DOI:10.3390/ph17101387
Chiara Montemitro, Alessio Mosca, Stefania Chiappini, Andrea Miuli, Fabrizio Schifano, Maria Josè Gordillo Montano, Cristina Merino Del Villar, Rita Allegretti, Carlotta Marrangone, Gilberto Di Petta, Domenico De Berardis, Mauro Pettorruso, Giovanni Martinotti
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Abstract

Background: illegal drugs significantly contribute to global health issues, with health complications often occurring not only in regular users with Substance Use Disorders (SUDs) but also in first-time and occasional users.

Methods: this study examines five clinical cases from a public hospital in Ibiza, Spain, where patients presented with acute psychiatric symptoms due to recreational drug use.

Results: Contrary to previous studies on SUDs, our patients typically had higher education levels and stable employment. Most of them used multiple substances, with cannabis, cocaine, and alcohol being the most frequently used. There was also a common occurrence of consuming drugs with uncertain contents. Upon admission, typical symptoms included aggression, hallucinations, mood swings, and disorientation in time and space.

Conclusions: Our findings underscore the significant mental health risks posed by illicit drugs, even for individuals with no prior psychiatric history. Factors like the drug's potency, frequency and amount of use, past mental health issues, personality traits, and previous traumatic experiences might influence the onset of these symptoms.

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俱乐部毒品与精神病治疗结果:来自西班牙的描述性病例系列。
背景:非法药物严重危害全球健康问题,其健康并发症不仅经常发生在有药物使用障碍(SUD)的常客身上,也经常发生在首次和偶尔吸毒者身上。方法:本研究对西班牙伊维萨一家公立医院的五个临床病例进行了研究,这些患者因使用娱乐性药物而出现急性精神症状:与以往的 SUDs 研究相反,我们的患者通常具有较高的教育水平和稳定的工作。他们中的大多数人使用多种药物,其中最常使用的是大麻、可卡因和酒精。此外,服用成分不确定的药物的情况也很常见。入院时的典型症状包括攻击行为、幻觉、情绪波动和时空错乱:我们的研究结果强调了非法药物对精神健康造成的巨大风险,即使是对以前没有精神病史的人也是如此。药物的效力、使用频率和数量、以往的精神健康问题、个性特征和以往的创伤经历等因素可能会影响这些症状的出现。
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来源期刊
Pharmaceuticals
Pharmaceuticals Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
6.10
自引率
4.30%
发文量
1332
审稿时长
6 weeks
期刊介绍: Pharmaceuticals (ISSN 1424-8247) is an international scientific journal of medicinal chemistry and related drug sciences.Our aim is to publish updated reviews as well as research articles with comprehensive theoretical and experimental details. Short communications are also accepted; therefore, there is no restriction on the maximum length of the papers.
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