Study of the Arrhythmogenic Profile of Dogs with Myxomatous Mitral Valve Disease in Stages B1 and B2.

IF 2 2区农林科学 Q2 VETERINARY SCIENCES Veterinary Sciences Pub Date : 2024-10-01 DOI:10.3390/vetsci11100467

Beatriz Almeida Santos, Jaqueline Valença Corrêa, Carolina Dragone Latini, Miriam Harumi Tsunemi, Angélica Alfonso, Luiz Henrique de Araújo Machado, Maria Lucia Gomes Lourenço

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Abstract

Myxomatous mitral valve disease (MMVD) is the most prevalent cardiac disease in dogs. This study aimed to compare the arrhythmogenic profile and heart rate variability (HRV) of dogs with MMVD in stages B1 and B2. Electrocardiographic exams and the medical records of 60 dogs were analyzed, and HRV, P wave dispersion, QT interval dispersion, and QT interval instability parameters were determined. The results showed significantly increased values in stage B2 compared with stage B1 (p < 0.05) regarding P wave maximum and minimum duration (Pmax and Pmin) and short-term instability (STI). In contrast, no statistically significant differences were observed regarding HRV parameters, P wave dispersion, or QT interval dispersion. Our findings showed that cardiac remodeling in stage B2 could not significantly alter the sympathovagal balance and showed little interference with the predisposition of arrhythmias in dogs with MMVD.

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研究B1期和B2期肌瘤性二尖瓣病犬的致心律失常特征。

肌瘤性二尖瓣病（MMVD）是犬中最常见的心脏疾病。本研究旨在比较二尖瓣肌瘤病 B1 期和 B2 期犬的心律失常特征和心率变异性（HRV）。研究人员分析了 60 只犬的心电图检查和病历，并测定了心率变异、P 波频散、QT 间期频散和 QT 间期不稳定性参数。结果显示，与 B1 期相比，B2 期的 P 波最大和最小持续时间（Pmax 和 Pmin）以及短期不稳定性（STI）值明显增加（P < 0.05）。相比之下，在心率变异参数、P 波弥散和 QT 间期弥散方面未观察到有统计学意义的差异。我们的研究结果表明，B2期的心脏重塑不会显著改变交感-迷走平衡，对MMVD犬的心律失常易感性几乎没有影响。

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来源期刊

Veterinary Sciences VETERINARY SCIENCES-

CiteScore

2.90

自引率

8.30%

发文量

612

审稿时长

6 weeks

期刊介绍： Veterinary Sciences is an international and interdisciplinary scholarly open access journal. It publishes original that are relevant to any field of veterinary sciences, including prevention, diagnosis and treatment of disease, disorder and injury in animals. This journal covers almost all topics related to animal health and veterinary medicine. Research fields of interest include but are not limited to: anaesthesiology anatomy bacteriology biochemistry cardiology dentistry dermatology embryology endocrinology epidemiology genetics histology immunology microbiology molecular biology mycology neurobiology oncology ophthalmology parasitology pathology pharmacology physiology radiology surgery theriogenology toxicology virology.