Pathophysiology of Congestion in Heart Failure: A Contemporary Review.

IF 4.2 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Cardiac Failure Review Pub Date : 2024-09-25 eCollection Date: 2024-01-01 DOI:10.15420/cfr.2024.07
Marko Kumric, Tina Ticinovic Kurir, Josko Bozic, Anteo Bradaric Slujo, Duska Glavas, Dino Miric, Mislav Lozo, Jaksa Zanchi, Josip A Borovac
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Abstract

Acutely decompensated heart failure is one of the leading causes of hospitalisation worldwide, with a significant majority of these cases attributed to congestion. Although congestion is commonly mistaken for volume overload, evidence suggests that decompensation can occur without significant water accumulation, being attributed to volume redistribution. Yet, the distinction between intravascular and extravascular congestion in heart failure often blurs, as patients frequently exhibit overlapping features of both, and as patients may transition between phenotypes over time. Considering that differentiation between intravascular and extravascular congestion can lead to different management strategies, the aim of this review was to delineate the pathophysiological nuances between the two, as well as their correlation with clinical, biochemical and imaging indices.

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心力衰竭充血的病理生理学:当代回顾。
急性失代偿性心力衰竭是全球住院治疗的主要原因之一,其中绝大多数病例归因于充血。虽然充血通常被误认为是容量超负荷,但有证据表明,失代偿发生时并不会出现明显的水分积聚,而是由于容量重新分配所致。然而,心衰患者血管内充血和血管外充血之间的区别往往很模糊,因为患者经常表现出两者的重叠特征,而且随着时间的推移,患者可能会在不同表型之间转换。考虑到区分血管内充血和血管外充血可导致不同的管理策略,本综述旨在阐明两者在病理生理学上的细微差别,以及它们与临床、生化和影像学指标的相关性。
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来源期刊
CiteScore
5.60
自引率
0.00%
发文量
31
审稿时长
9 weeks
期刊最新文献
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