A Single-Centre Analysis of Surgical Techniques for Myelomeningocele Closure: Methods, Outcomes, and Complications.

IF 1.7 Q2 MEDICINE, GENERAL & INTERNAL Clinics and Practice Pub Date : 2024-09-29 DOI:10.3390/clinpract14050162
Alina Roxana Cehan, Dorin Constantin Dorobanțu, Corina Ionela Tamas, Vlad Dimitrie Cehan, Flaviu Tamas, Adrian Balasa
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Abstract

(1) Background: Neural tube defects are a prevalent cause of congenital malformations, myelomeningocele (MMC) being the most severe form. This study evaluates the clinical outcome and postoperative-associated complications following MMC surgical closures, focusing on the following three techniques: direct suture (DS); VY advancement flap (VYF); and Limberg flap (LF). (2) Methods: A retrospective observational study was conducted from March 2015 to February 2023, and the inclusion criteria were newborns who underwent lumbosacral MMC within 24 h of birth. (3) Results: Out of 20 cases, 45% underwent DS closure; 25% underwent VY-F closure; 15% underwent LF closure, and 15% (n = 3) underwent combined flap closure. A significant statistical correlation was observed between intracranial hypertension (IH), the need for external ventricular drainage (EVD), and DS closure type. In the DS group, 60% of patients required EVD (p = 0.041), and 90% had IH (p = 0.027). CSF fistula was present in 40% of LF cases and 30% of DS cases, while wound dehiscence was observed in 60% of LF cases and 30% of DS cases. (4) Conclusions: Our study demonstrated that DS was linked to higher rates of complications. The VY-F is the safest method for closing MMC defects.

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对脊髓空洞闭合手术技术的单中心分析:方法、结果和并发症。
(1) 背景:神经管畸形是先天性畸形的常见病因之一,而髓母管畸形(MMC)是最严重的先天性畸形。本研究评估了 MMC 手术闭合后的临床效果和术后相关并发症,重点关注以下三种技术:直接缝合(DS)、VY 推进皮瓣(VYF)和 Limberg 皮瓣(LF)。(2) 方法:2015年3月至2023年2月进行了一项回顾性观察研究,纳入标准为出生后24小时内接受腰骶部MMC手术的新生儿。(3)结果:在20例病例中,45%进行了DS闭合;25%进行了VY-F闭合;15%进行了LF闭合,15%(n = 3)进行了联合皮瓣闭合。颅内高压(IH)、脑室外引流(EVD)需求和 DS 闭合类型之间存在明显的统计学相关性。在 DS 组中,60% 的患者需要 EVD(p = 0.041),90% 的患者有 IH(p = 0.027)。40% 的 LF 病例和 30% 的 DS 病例出现脑脊液瘘,而 60% 的 LF 病例和 30% 的 DS 病例出现伤口裂开。(4) 结论:我们的研究表明,DS 与较高的并发症发生率有关。VY-F 是关闭 MMC 缺口最安全的方法。
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来源期刊
Clinics and Practice
Clinics and Practice MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
4.30%
发文量
91
审稿时长
10 weeks
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