Quantitative lung ultrasound findings correlate with radial alveolar count in experimental bronchopulmonary dysplasia.

IF 3.4 Q2 Medicine Ultrasound Journal Pub Date : 2024-10-28 DOI:10.1186/s13089-024-00389-y
Chiara Catozzi, Angelo Modena, Matteo Storti, Francesca Ricci, Gino Villetti, Daniele De Luca
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Abstract

We investigated the relationship between the degree of alveolarization and ultrasound-assessed lung aeration in a validated preterm rabbit model of experimental bronchopulmonary dysplasia (BPD). Lung ultrasound findings were heterogeneously abnormal and consisted of zones with interstitial, interstitial-alveolar or consolidated patterns. The median radial alveolar count was 10.1 [8.4-11.5], 7.8 [6.1-9] and 7.3 [1.8-10.1] in rabbits with interstitial, interstitial-alveolar or consolidated ultrasound pattern, respectively (overall p = 0.036). Alveolar count and lung ultrasound score were significantly correlated (ρ = - 0.044 (95%CI: - 1; - 0.143), p = 0.009; τ-b = - 0.362 (95%CI: - 0.6; - 0.1), p = 0.017).

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肺部定量超声波检查结果与实验性支气管肺发育不良的径向肺泡数相关。
我们研究了实验性支气管肺发育不良(BPD)早产兔模型中肺泡化程度与超声评估的肺通气性之间的关系。肺部超声波检查结果呈现异质性异常,包括间质区、间质-肺泡区或合并区。间质型、间质-肺泡型或合并型兔子的径向肺泡数中位数分别为 10.1 [8.4-11.5]、7.8 [6.1-9]和 7.3 [1.8-10.1](总 p = 0.036)。肺泡计数与肺部超声评分呈显著相关性(ρ = - 0.044 (95%CI: - 1; - 0.143), p = 0.009; τ-b = - 0.362 (95%CI: - 0.6; - 0.1), p = 0.017)。
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来源期刊
Ultrasound Journal
Ultrasound Journal Health Professions-Radiological and Ultrasound Technology
CiteScore
6.80
自引率
2.90%
发文量
45
审稿时长
22 weeks
期刊最新文献
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