Musculoskeletal melioidosis-a retrospective review of 22 cases from a tertiary care centre in South Tamilnadu

IF 1.4 4区 医学 Q4 IMMUNOLOGY Indian Journal of Medical Microbiology Pub Date : 2024-11-01 DOI:10.1016/j.ijmmb.2024.100750
G. Vithiya , G. Rajalakshmi Preethi , P. Shunmuga Sundaram , T. Rajendran
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Abstract

A retrospective review of culture confirmed musculoskeletal melioidosis reported between December 2014 and February 2024 was conducted. 22 of 100 patients with culture proven melioidosis infection had musculoskeletal involvement. Median age was 47 years with 95.4 % being males. Osteomyelitis, septic arthritis and septic arthritis along with adjacent osteomyelitis were observed in 12, 9 and 4 cases respectively. All isolates were susceptible to meropenem and susceptible increased exposure to ceftazidime, doxycycline and cotrimoxazole. Twelve patients underwent surgical procedures. Four patients who died due to septicemia had multisystem involvement with positive blood cultures.
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南泰米尔纳德邦一家三级医疗中心的 22 个病例的回顾性研究。
我们对 2014 年 12 月至 2024 年 2 月期间报告的经培养证实的肌肉骨骼类美拉德病进行了回顾性研究。在100名经培养证实感染了类鼻疽的患者中,有22名患者的肌肉骨骼受累。中位年龄为47岁,95.4%为男性。骨髓炎、化脓性关节炎和化脓性关节炎合并邻近骨髓炎的病例分别为 12 例、9 例和 4 例。所有分离菌株均对美罗培南敏感,对头孢他啶、强力霉素和复方新诺明的敏感性增加。12 名患者接受了外科手术。因脓毒症死亡的四名患者涉及多个系统,血液培养呈阳性。
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来源期刊
CiteScore
2.20
自引率
0.00%
发文量
154
审稿时长
73 days
期刊介绍: Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.
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