Use of Postoperative Radiotherapy and Multiple Adjuvant Treatments After Surgical Removal of a Giant Retroauricular Keloid in a Pediatric Patient.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-11-03 DOI:10.1111/pde.15787
Joaquín Espiñeira Sicre, Marta Ivars, Oliver Haag Heinz, Peter Wienberg Ludwig, Josep Isern Verdun, Eulalia Baselga Torres
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Abstract

The use of postoperative radiotherapy (PORT) for the treatment of keloids in the pediatric population is rare, despite being a common pathology at this age. Recurrences after surgery are very common. The absence of a standardized protocol for the management of recurrent keloids further complicates therapeutic decision-making. Here, we present a clinical case involving a recurrent giant retroauricular keloid in a pediatric patient, demonstrating a satisfactory response to a comprehensive approach involving surgery, PORT, and periodic injections of 5-fluorouracil with corticosteroid. We believe that reporting this case adds value as a potential therapeutic option in the absence of established protocols for recurrent keloids in pediatric patients.

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小儿巨大耳后瘢痕疙瘩手术切除后的术后放疗和多重辅助治疗
尽管瘢痕疙瘩是小儿常见的病症,但在小儿群体中使用术后放疗(PORT)治疗瘢痕疙瘩的情况却很少见。术后复发非常常见。由于缺乏治疗复发性瘢痕疙瘩的标准化方案,使得治疗决策变得更加复杂。在此,我们介绍了一例涉及复发性巨大耳后瘢痕疙瘩的儿科临床病例,该病例对包括手术、PORT 和定期注射 5-氟尿嘧啶与皮质类固醇在内的综合治疗方法的反应令人满意。我们认为,在缺乏针对儿童患者复发性瘢痕疙瘩的既定方案的情况下,报告这一病例可作为一种潜在的治疗选择,从而增加其价值。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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