Fiber anatomy and histological characteristics of the innervation of the triangular fibrocartilage complex.

IF 1.4 4区医学 Q2 Medicine Surgical and Radiologic Anatomy Pub Date : 2024-11-04 DOI:10.1007/s00276-024-03443-5

Tonglong Xu, Xiaoyun Pan, Jingyi Mi

{"title":"Fiber anatomy and histological characteristics of the innervation of the triangular fibrocartilage complex.","authors":"Tonglong Xu, Xiaoyun Pan, Jingyi Mi","doi":"10.1007/s00276-024-03443-5","DOIUrl":null,"url":null,"abstract":"Purpose: To evaluate the precise origin of sensory nerves through gross anatomical study of the TFCC, synthesized alongside imaging and histological techniques.Method: Six cadaveric forearm specimens were obtained to map the course and branches of the ulnar nerve through macrodissection. Immunohistochemical staining targeting PGP 9.5 and type IV collagen was performed on frozen TFCC sections to visualize nerve fibers microscopically. Computed tomography, magnetic resonance imaging, and arthrography findings were also reviewed.Results: At the macroscopic level, the articular branches supplying the TFCC originated predominantly from the dorsal branch of the ulnar nerve. Microscopic analysis revealed positive PGP 9.5 expression and discernible neural marker expression, signifying fine nerve fiber ingrowth within the TFCC. Imaging modalities aided the diagnosis of TFCC lesions. The dorsal cutaneous branch of the ulnar nerve, medial cutaneous nerve of the forearm, and volar sensory branch of the ulnar nerve emerged as the principal nerves innervating the TFCC.Conclusions: This study provides anatomical evidence that the TFCC receives innervation from branches of the ulnar nerve and contains sensory nerve fibers. These findings enhance understanding of potential neuropathic pain mechanisms in TFCC injuries and offer insights to guide surgical interventions. Further investigations are warranted to elucidate the clinical implications.","PeriodicalId":49461,"journal":{"name":"Surgical and Radiologic Anatomy","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgical and Radiologic Anatomy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00276-024-03443-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To evaluate the precise origin of sensory nerves through gross anatomical study of the TFCC, synthesized alongside imaging and histological techniques.

Method: Six cadaveric forearm specimens were obtained to map the course and branches of the ulnar nerve through macrodissection. Immunohistochemical staining targeting PGP 9.5 and type IV collagen was performed on frozen TFCC sections to visualize nerve fibers microscopically. Computed tomography, magnetic resonance imaging, and arthrography findings were also reviewed.

Results: At the macroscopic level, the articular branches supplying the TFCC originated predominantly from the dorsal branch of the ulnar nerve. Microscopic analysis revealed positive PGP 9.5 expression and discernible neural marker expression, signifying fine nerve fiber ingrowth within the TFCC. Imaging modalities aided the diagnosis of TFCC lesions. The dorsal cutaneous branch of the ulnar nerve, medial cutaneous nerve of the forearm, and volar sensory branch of the ulnar nerve emerged as the principal nerves innervating the TFCC.

Conclusions: This study provides anatomical evidence that the TFCC receives innervation from branches of the ulnar nerve and contains sensory nerve fibers. These findings enhance understanding of potential neuropathic pain mechanisms in TFCC injuries and offer insights to guide surgical interventions. Further investigations are warranted to elucidate the clinical implications.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

三角纤维软骨复合体的纤维解剖和神经支配组织学特征。

目的：通过对 TFCC 的大体解剖研究，结合影像学和组织学技术，评估感觉神经的精确起源：方法：获取六具尸体前臂标本，通过大体解剖绘制尺神经的走向和分支图。在 TFCC 冷冻切片上进行针对 PGP 9.5 和 IV 型胶原的免疫组化染色，以便在显微镜下观察神经纤维。此外，还回顾了计算机断层扫描、磁共振成像和关节造影的结果：宏观上，供应 TFCC 的关节分支主要来自尺神经背侧支。显微镜分析显示 PGP 9.5 表达阳性，并有明显的神经标记表达，表明 TFCC 内有细小的神经纤维生长。成像模式有助于诊断 TFCC 病变。尺神经背皮支、前臂内侧皮神经和尺神经外侧感觉支是支配 TFCC 的主要神经：本研究提供了解剖学证据，证明 TFCC 接受尺神经分支的支配，并含有感觉神经纤维。这些发现加深了人们对 TFCC 损伤的潜在神经病理性疼痛机制的理解，并为指导手术干预提供了启示。还需要进一步研究以阐明其临床意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Surgical and Radiologic Anatomy Medicine-Pathology and Forensic Medicine

CiteScore

2.40

自引率

14.30%

发文量

期刊介绍： Anatomy is a morphological science which cannot fail to interest the clinician. The practical application of anatomical research to clinical problems necessitates special adaptation and selectivity in choosing from numerous international works. Although there is a tendency to believe that meaningful advances in anatomy are unlikely, constant revision is necessary. Surgical and Radiologic Anatomy, the first international journal of Clinical anatomy has been created in this spirit. Its goal is to serve clinicians, regardless of speciality-physicians, surgeons, radiologists or other specialists-as an indispensable aid with which they can improve their knowledge of anatomy. Each issue includes: Original papers, review articles, articles on the anatomical bases of medical, surgical and radiological techniques, articles of normal radiologic anatomy, brief reviews of anatomical publications of clinical interest. Particular attention is given to high quality illustrations, which are indispensable for a better understanding of anatomical problems. Surgical and Radiologic Anatomy is a journal written by anatomists for clinicians with a special interest in anatomy.