Barks and leaves of Lauraceae plants as anti-acne.

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY Pakistan journal of pharmaceutical sciences Pub Date : 2024-09-01
Nur Adliani, Defri Rizaldy, Marlia Singgih Wibowo, Rachmat Mauludin, - Sukrasno
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Abstract

Acne vulgaris is an inflammatory skin disease caused by several factors, including an imbalance of microorganisms compared to the normal microbial distribution in healthy tissue. The Lauraceae family which have been reported from antiseptic. This research was conducted to assayed the compounds, the biological activity of the Lauraceae plant essential oil (EO) could against microbes. EO Were isolated by steam water distillation and had antibacterial effects were analyzed by microdilution in broth medium and EO compounds were analyzed by GC-MS. The most abundant components present in N. cassia leaves cinnamyl acetate, N. cassia bark beta-citronellol, linalool, e-citral and geraniol, C. verum bark eugenol, C. burmanni leaves linalool, alpha-terpineol, eucalyptol, cinnamaldehyde, caryophyllene, cinnamyl, leaves of Cinnamomum camphora contains camphor. The highest antimicrobial activity against C. acnes was given by oil from the leaves and bark of Neolitsea cassia, against S. aureus and by oil from the bark of C. verum and N. cassia and C. burmannii leaves. The oil of C. champora leaves gave better activity than the barks against these microbes. It was found that the leaves of C. champora had the highest yield of oil compared to the other part of Lauraceae plants tested and it has a strong antibacterial activity toward microbes commonly present in acne vulgaris.

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月桂科植物的树皮和叶子可抗痘。
寻常痤疮是一种炎症性皮肤病,由多种因素引起,包括与健康组织中正常的微生物分布相比,微生物分布失衡。据报道,月桂科植物具有杀菌作用。这项研究的目的是化验月桂科植物精油(EO)中的化合物以及它们对微生物的生物活性。在肉汤培养基中用微量稀释法分析了通过水蒸气蒸馏分离出的具有抗菌作用的精油,并用气相色谱-质谱法分析了精油化合物。决明子叶中含量最多的成分是乙酸肉桂酯,决明子树皮中含量最多的成分是 beta-香茅醇、芳樟醇、柠檬醛和香叶醇,茜草树皮中含量最多的成分是丁香酚,布曼尼树叶中含量最多的成分是芳樟醇、α-松油醇、桉叶油醇、肉桂醛、石竹烯、肉桂基,樟树叶中含量最多的成分是樟脑。决明子叶和树皮萃取的精油对痤疮丙酸杆菌的抗菌活性最高,对金黄色葡萄球菌的抗菌活性也最高,朱砂、决明子叶和布尔曼尼叶萃取的精油对金黄色葡萄球菌的抗菌活性也最高。香蒲叶油对这些微生物的活性优于树皮。研究发现,与测试的其他部分月桂科植物相比,香蒲叶的产油量最高,对常见于寻常痤疮的微生物具有很强的抗菌活性。
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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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