Reduced resting-state periodic beta power in adults who stutter is related to sensorimotor control of speech execution

Abstract

Objective

The primary aim of the current study was to determine whether adults who stutter (AWS) present with anomalous periodic beta (β) rhythms when compared to typically fluent adults in the eyes-open resting state. A second aim was to determine whether lower β power in the RS is related to a measure of β event-related desynchronization (ERD) during syllable sequence execution.

Methods

EEG data was collected from 128 channels in a 5 min, eyes-open resting state condition and from a syllable sequence repetition task. Temporal independent component analysis (ICA) was used to separate volume conducted EEG sources and to find a set of component weights common to the RS and syllable repetition task. Both traditional measures of power spectral density (PSD) and parameterized spectra were computed for components showing peaks in the β band (13–30 Hz). Parameterization was used to evaluate separable components adjusted for the 1/f part of the spectrum.

Results

ICA revealed frontal-parietal midline and lateral sensorimotor (μ) components common to the RS and a syllable repetition task with peaks in the β band. The entire spectrum for each component was modeled using the FOOOF algorithm. Independent samples t-tests revealed significantly lower periodic β in midline central-parietal and lateral sensorimotor components in AWS. Regression analysis suggested a significant relationship between left periodic sensorimotor β power in the RS and ERD during syllable sequence execution.

Conclusions

Findings suggest that periodic β peaks in the spectrum are related to hypothesized underlying pathophysiological differences in stuttering, including midline rhythms associated the default mode network (DMN) and lateral sensorimotor rhythms associated with the control of movement.