Eman Yossri Frag, Asmaa M. Mahmoud, Marwa El-Badry Mohamed
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引用次数: 0
Abstract
It is shown that interaction of electron donor tioconazole (TCZ) with π acceptors chloroanilic acid, 2,3-dichloro-5,6-dicyano-1,4-benzoquinone, and picric acid leads to formation of the charge transfer complexes. The obtained complexes are characterized by spectral methods, and specific features of their structure are revealed by DFT. It is found that such complexes possess cytotoxic activity against breast cancer line (MCF-7), and their efficiency on IC50 criterion exceeds the efficiency of the individual TCZ.
期刊介绍：
Theoretical and Experimental Chemistry is a journal for the rapid publication of research communications and reviews on modern problems of physical chemistry such as:
a) physicochemical bases, principles, and methods for creation of novel processes, compounds, and materials;
b) physicochemical principles of chemical process control, influence of external physical forces on chemical reactions;
c) physical nanochemistry, nanostructures and nanomaterials, functional nanomaterials, size-dependent properties of materials.
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