Emerging Imaging Techniques for Atherosclerosis in Systemic Immune-Mediated Inflammatory Conditions.

IF 7.4 1区 医学 Q1 HEMATOLOGY Arteriosclerosis, Thrombosis, and Vascular Biology Pub Date : 2024-11-14 DOI:10.1161/ATVBAHA.124.321202
George Markousis-Mavrogenis, Muzzamal Habib, Daniel M Huck, Florian Andre, Henning Steen, Monica Mukherjee, Sophie I Mavrogeni, Brittany Weber
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Abstract

Atherosclerosis affects patients with systemic immune-mediated inflammatory diseases at an increased rate compared with the general population. In recent years, our understanding of the pathophysiology of atherosclerosis has advanced considerably. Nevertheless, cardiovascular imaging modalities that can adequately assess the biological background of atherosclerosis have not reached widespread clinical adoption. Novel developments in cardiac imaging have the potential to enhance the diagnostic yield of these modalities further while providing essential insights into the anatomy, composition, and biology of atherosclerotic lesions. In this review, we highlight some of the latest developments in the field for the evaluation of atherosclerosis using advances in echocardiography, computed tomography, positron emission tomography, and cardiovascular magnetic resonance. Additionally, we discuss evidence specifically in patients with immune-mediated inflammatory diseases and outline unmet research needs for future development.

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全身免疫性炎症中动脉粥样硬化的新兴成像技术。
与普通人群相比,动脉粥样硬化对全身免疫介导的炎症性疾病患者的影响更大。近年来,我们对动脉粥样硬化病理生理学的认识有了长足的进步。然而,能够充分评估动脉粥样硬化生物学背景的心血管成像模式尚未在临床上得到广泛应用。心脏成像技术的新发展有可能进一步提高这些模式的诊断率,同时提供对动脉粥样硬化病变的解剖、组成和生物学的重要见解。在这篇综述中,我们将重点介绍利用超声心动图、计算机断层扫描、正电子发射断层扫描和心血管磁共振技术的进步评估动脉粥样硬化的一些最新进展。此外,我们还特别讨论了免疫介导的炎症性疾病患者的证据,并概述了未来发展中尚未满足的研究需求。
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来源期刊
CiteScore
15.60
自引率
2.30%
发文量
337
审稿时长
2-4 weeks
期刊介绍: The journal "Arteriosclerosis, Thrombosis, and Vascular Biology" (ATVB) is a scientific publication that focuses on the fields of vascular biology, atherosclerosis, and thrombosis. It is a peer-reviewed journal that publishes original research articles, reviews, and other scholarly content related to these areas. The journal is published by the American Heart Association (AHA) and the American Stroke Association (ASA). The journal was published bi-monthly until January 1992, after which it transitioned to a monthly publication schedule. The journal is aimed at a professional audience, including academic cardiologists, vascular biologists, physiologists, pharmacologists and hematologists.
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