Nguyen Huy Hoang, Do Thi Trang, Ngo Anh Bang, Pham Hai Yen, Duong Thi Dung, Nguyen Xuan Nhiem, Le Thi Huyen, Phan Thi Thanh Huong, Duong Thi Hai Yen, Bui Huu Tai, Phan Van Kiem
{"title":"Three New Sesquiterpenes from the Leaves of Aglaia elaeagnoidea with NO Inhibitory Activity.","authors":"Nguyen Huy Hoang, Do Thi Trang, Ngo Anh Bang, Pham Hai Yen, Duong Thi Dung, Nguyen Xuan Nhiem, Le Thi Huyen, Phan Thi Thanh Huong, Duong Thi Hai Yen, Bui Huu Tai, Phan Van Kiem","doi":"10.1002/cbdv.202402159","DOIUrl":null,"url":null,"abstract":"<p><p>Aglanoideas A-C (1-3), three undescribed sesquiterpenes and eleven known compounds (4-14) were isolated from the leaves of Aglaia elaeagnoidea. Their structures including absolute configurations were characterized by using IR, HR-ESI-MS, NMR, and experimental and calculating ECD methods. Compounds 3-5 and 7 showed moderate nitric oxide inhibitory activity with IC50 value ranging from 53.7 to 72.5 µM.</p>","PeriodicalId":9878,"journal":{"name":"Chemistry & Biodiversity","volume":" ","pages":"e202402159"},"PeriodicalIF":2.3000,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry & Biodiversity","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/cbdv.202402159","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Aglanoideas A-C (1-3), three undescribed sesquiterpenes and eleven known compounds (4-14) were isolated from the leaves of Aglaia elaeagnoidea. Their structures including absolute configurations were characterized by using IR, HR-ESI-MS, NMR, and experimental and calculating ECD methods. Compounds 3-5 and 7 showed moderate nitric oxide inhibitory activity with IC50 value ranging from 53.7 to 72.5 µM.
期刊介绍：
Chemistry & Biodiversity serves as a high-quality publishing forum covering a wide range of biorelevant topics for a truly international audience. This journal publishes both field-specific and interdisciplinary contributions on all aspects of biologically relevant chemistry research in the form of full-length original papers, short communications, invited reviews, and commentaries. It covers all research fields straddling the border between the chemical and biological sciences, with the ultimate goal of broadening our understanding of how nature works at a molecular level.
Since 2017, Chemistry & Biodiversity is published in an online-only format.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
