{"title":"Anti N-Methyl-D-Aspartate receptor encephalitis during pregnancy: a case report.","authors":"Leïa Kennel, Dominique Luton, Florence Gressier, Chloé Daffos, Emmanuelle Corruble, Laure Julé, Jean-Baptiste Brunet de Courssou, Claire Szmulewicz","doi":"10.1016/j.jogoh.2024.102876","DOIUrl":null,"url":null,"abstract":"<p><p>Anti-N-methyl-D-aspartate receptor (NMDA-R) encephalitis is an immune-mediated encephalitis that primarily affects young women. Due to the psychiatric and neurological symptoms, the diagnosis can be challenging, especially during pregnancy. During pregnancy, treatments must take into account the fetal and neonatal risk and the risk of premature delivery. We report a case of anti-NMDA encephalitis in a 31-years-old, 30 weeks pregnant women characterized by predominantly psychiatric symptoms, associated with ovarian teratoma. First-line treatments have led to an improvement in symptoms, allowing the pregnancy to be carried to term and a vaginal delivery.</p>","PeriodicalId":15871,"journal":{"name":"Journal of gynecology obstetrics and human reproduction","volume":null,"pages":null},"PeriodicalIF":1.7000,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of gynecology obstetrics and human reproduction","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jogoh.2024.102876","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Anti-N-methyl-D-aspartate receptor (NMDA-R) encephalitis is an immune-mediated encephalitis that primarily affects young women. Due to the psychiatric and neurological symptoms, the diagnosis can be challenging, especially during pregnancy. During pregnancy, treatments must take into account the fetal and neonatal risk and the risk of premature delivery. We report a case of anti-NMDA encephalitis in a 31-years-old, 30 weeks pregnant women characterized by predominantly psychiatric symptoms, associated with ovarian teratoma. First-line treatments have led to an improvement in symptoms, allowing the pregnancy to be carried to term and a vaginal delivery.
期刊介绍：
Formerly known as Journal de Gynécologie Obstétrique et Biologie de la Reproduction, Journal of Gynecology Obstetrics and Human Reproduction is the official Academic publication of the French College of Obstetricians and Gynecologists (Collège National des Gynécologues et Obstétriciens Français / CNGOF).
J Gynecol Obstet Hum Reprod publishes monthly, in English, research papers and techniques in the fields of Gynecology, Obstetrics, Neonatology and Human Reproduction: (guest) editorials, original articles, reviews, updates, technical notes, case reports, letters to the editor and guidelines.
Original works include clinical or laboratory investigations and clinical or equipment reports. Reviews include narrative reviews, systematic reviews and meta-analyses.
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